Stereoselective Synthesis of Highly Substituted O-Heterocycles via Matteson Homologation: A Ring-Closing Metathesis Approach

被引：2

作者：

Kinsinger, Thorsten ^{[1
]}

Schaefer, Patrick ^{[1
]}

Kazmaier, Uli ^{[1
]}

机构：

[1] Saarland Univ, Organ Chem 1, D-66123 Saarbrucken, Germany

来源：

ORGANIC LETTERS | 2023年 / 25卷 / 18期

关键词：

PROTECTED SIDE-CHAIN; BORONIC ESTERS; NATURAL-PRODUCTS; RUCL2(=CHR)(PR(3))(2); DERIVATIVES; COMPLEXES; MACROLIDE; CATALYSTS;

D O I：

10.1021/acs.orglett.3c01099

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Matteson homologations of chiral boronic esters with the aid of unsaturated nucleophiles are powerful for gaining access to a range of different O-heterocycles via subsequent ring-closing metatheses. Using this protocol, six-to eight-membered rings become available and almost any position of the ring can be substituted and/or functionalized.

引用

页码：3303 / 3307

页数：5

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