Mapping the functions of IgM antibodies in atherosclerotic cardiovascular disease

被引:3
|
作者
Deroissart, Justine [1 ]
Binder, Christoph J. [1 ]
机构
[1] Med Univ Vienna, Dept Lab Med, Vienna, Austria
基金
奥地利科学基金会;
关键词
OXIDATION-SPECIFIC EPITOPES;
D O I
10.1038/s41569-023-00888-w
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
IgM antibodies have gained much attention as risk markers of atherosclerotic cardiovascular disease, but the exact antigenic determinants and the full spectrum of functions remain to be defined. A better understanding of the potentially diverse nature of the antigens that they recognize will help to dissect the function of IgM in atherosclerosis.
引用
收藏
页码:433 / 434
页数:2
相关论文
共 25 条
  • [1] Role of Antibodies and Their Specificities in Atherosclerotic Cardiovascular Disease
    Deroissart, Justine
    Binder, Christoph J.
    Porsch, Florentina
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2024, 44 (10) : 2154 - 2168
  • [2] The Spectrum of B Cell Functions in Atherosclerotic Cardiovascular Disease
    Smeets, Diede
    Gistera, Anton
    Malin, Stephen G.
    Tsiantoulas, Dimitrios
    FRONTIERS IN CARDIOVASCULAR MEDICINE, 2022, 9
  • [3] Lipoprotein(a) in atherosclerotic cardiovascular disease and proprotein convertase subtilisin/kexin-type 9 inhibitors
    Lian, Ping-an
    Zhu, Wen-qiang
    Zhao, Wei-xin
    Huang, Piao-piao
    Ran, Juan-li
    Tang, Ya-xin
    Huang, Xian-sheng
    Li, Rong
    CLINICA CHIMICA ACTA, 2025, 565
  • [4] Natural IgM antibodies help fend off thrombosis
    Haskard, Dorian O.
    BLOOD, 2021, 137 (10) : 1280 - 1281
  • [5] ApoA1 and ApoA1-specific self-antibodies in cardiovascular disease
    Chistiakov, Dimitry A.
    Orekhov, Alexander N.
    Bobryshev, Yuri V.
    LABORATORY INVESTIGATION, 2016, 96 (07) : 708 - 718
  • [6] Fatal attractions that trigger inflammation and drive atherosclerotic disease
    Sharma, Hitesh
    Mossman, Karen
    Austin, Richard C.
    EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2024, 54 (05)
  • [7] Plasma levels of anti phosphocholine IgM antibodies are negatively correlated with bone mineral density in humans
    Palmieri, Michela
    Maraka, Spyridoula
    Spencer, Horace J.
    Thostenson, Jeff D.
    Dishongh, Katherine
    Knox, Micheal
    Ussery, Betty
    Byrd, Jesse
    Kuipers, Jacqueline K.
    Abedzadeh-Anaraki, Sanaz
    Duvoor, Chitharanjan
    Mao, Yuanjie
    Menon, Lakshmi
    Williams, James S.
    Manolagas, Stavros C.
    Jilka, Robert L.
    Ambrogini, Elena
    SCIENTIFIC REPORTS, 2025, 15 (01):
  • [8] Oxidized phospholipids in cardiovascular disease
    Tsimikas, Sotirios
    Witztum, Joseph L.
    NATURE REVIEWS CARDIOLOGY, 2024, 21 (03) : 170 - 191
  • [9] IgM-Antibodies against Phosphorylcholine in Mothers and Normal or Low Birth Weight Term Newborn Infants
    Frostegard, Anna G.
    Sjoberg, Beatrice G.
    Frostegard, Johan
    Norman, Mikael
    PLOS ONE, 2014, 9 (09):
  • [10] Total fecal IgA levels increase and natural IgM antibodies decrease after gastric bypass surgery
    Istomin, Natalie
    Harma, Mari-Anne
    Akhi, Ramin
    Nissinen, Antti E.
    Savolainen, Markku J.
    Adeshara, Krishna
    Lehto, Markku
    Groop, Per-Henrik
    Koivukangas, Vesa
    Hukkanen, Janne
    Horkko, Sohvi
    APMIS, 2022, 130 (11) : 637 - 646