Changes in Principal Caregiver Mood Affects the Mood of the Parkinson's Disease Patient: The Vicious Cycle of Illness

被引：3

作者：

Santos-Garcia, Diego ^{[1
]}

de Deus Fonticoba, Teresa ^{[2
]}

Cores Bartolome, Carlos ^{[1
]}

Feal Painceiras, Maria J. ^{[1
]}

Cristina Iniguez-Alvarado, Maria ^{[1
]}

Diaz, Iago Garcia ^{[1
]}

Jesus, Silvia ^{[3
,4
]}

Teresa Buongiorno, Maria ^{[5
]}

Planellas, Lluis ^{[6
]}

Cosgaya, Marina ^{[7
]}

Garcia Caldentey, Juan ^{[8
]}

Caballol, Nuria ^{[9
]}

Legarda, Ines ^{[10
]}

Hernandez Vara, Jorge ^{[4
,11
]}

Cabo, Iria ^{[12
]}

Lopez Manzanares, Lydia ^{[13
]}

Gonzalez Aramburu, Isabel ^{[4
,14
]}

Avila Rivera, Maria A. ^{[15
]}

Gomez Mayordomo, Victor ^{[16
]}

Nogueira, Victor ^{[17
]}

Puente, Victor ^{[18
]}

Dotor Garcia-Soto, Julio ^{[19
]}

Borrue, Carmen ^{[20
]}

Solano Vila, Berta ^{[21
]}

Alvarez Sauco, Maria ^{[22
]}

Vela, Lydia ^{[23
]}

Escalante, Sonia ^{[24
]}

Cubo, Esther ^{[25
]}

Carrillo Padilla, Francisco ^{[26
]}

Martinez Castrillo, Juan C. ^{[27
]}

Sanchez Alonso, Pilar ^{[28
]}

Alonso Losada, Maria G. ^{[29
]}

Lopez Ariztegui, Nuria ^{[30
]}

Gaston, Itziar ^{[31
]}

Kulisevsky, Jaime ^{[4
,32
]}

Menendez Gonzalez, Manuel ^{[33
]}

Seijo, Manuel ^{[12
]}

Ruiz Martinez, Javier ^{[34
]}

Valero, Caridad ^{[35
]}

Kurtis, Monica ^{[36
]}

Gonzalez Ardura, Jessica ^{[37
]}

Redondo, Ruben Alonso ^{[38
]}

Ordas, Carlos ^{[39
]}

Lopez Diaz, Luis M. ^{[29
]}

McAfee, Darrian ^{[40
]}

Martinez-Martin, Pablo ^{[4
]}

Mir, Pablo ^{[3
,4
]}

机构：

[1] CHUAC, La Coruna, Spain

[2] CHUF, La Coruna, Spain

[3] Univ Seville, Inst Biomed Sevilla, Serv Neurol & Neurofisiol Clin,CSIC, Unidad Trastornos Movimiento,Hosp Univ Virgen Roc, Seville, Spain

[4] CIBERNED Ctr Invest Biomed Red Enfermedades Neuro, Madrid, Spain

[5] Hosp Univ Mutua Terrassa, Barcelona, Spain

[6] Clin Pilar, Barcelona, Spain

[7] Hosp Clin Barcelona, Barcelona, Spain

[8] Ctr Neurol Oms 42, Palma De Mallorca, Spain

[9] Hosp Moises Broggi, Consorci Sanitari Integral, Barcelona, Spain

[10] Hosp Univ Son Espases, Palma De Mallorca, Spain

[11] Hosp Univ Vall dHebron, Barcelona, Spain

[12] Complejo Hosp Univ Pontevedra CHOP, Pontevedra, Spain

[13] Hosp Univ La Princesa, Madrid, Spain

[14] Hosp Univ Marques Valdecilla, Santander, Spain

[15] Hosp Gen LHosp, Consorci Sanitari Integral, Barcelona, Spain

[16] Hosp Univ Clin San Carlos, Madrid, Spain

[17] Hosp Costa, Lugo, Spain

[18] Hosp Mar, Barcelona, Spain

[19] Hosp Univ Virgen Macarena, Seville, Spain

[20] Hosp Infanta Sofia, Madrid, Spain

[21] Inst Assistencia Sanitaria IAS, Inst Catala Salut, Girona, Spain

[22] Hosp Gen Univ Elche, Elche, Spain

[23] Fdn Hosp Alcorcon, Madrid, Spain

[24] Hosp Tortosa Verge Cinta HTVC, Tarragona, Spain

[25] Complejo Asistencial Univ Burgos, Burgos, Spain

[26] Hosp Univ Canarias, San Cristobal De Laguna, Santa Cruz De T, Spain

[27] Hosp Univ Ramon y Cajal, IRYCIS, Madrid, Spain

[28] Hosp Univ Puerta Hierro, Madrid, Spain

[29] Complejo Hosp Univ Vigo CHUVI, Hosp Alvaro Cunqueiro, Vigo, Spain

[30] Complejo Hosp Toledo, Toledo, Spain

[31] Complejo Hosp Navarra, Pamplona, Spain

[32] Hosp Santa Creu & Sant Pau, Barcelona, Spain

[33] Hosp Univ Cent Asturias, Oviedo, Spain

[34] Hosp Univ Donostia, San Sebastian, Spain

[35] Hosp Arnau Vilanova, Valencia, Spain

[36] Hosp Ruber Int, Madrid, Spain

[37] Hosp Cabuenes, Gijon, Spain

[38] Univ Lucus Augusti HULA, Lugo, Spain

[39] Hosp Rey Juan Carlos, Madrid, Spain

[40] Univ Maryland, Sch Med, Baltimore, MD 21201 USA

来源：

JOURNAL OF PARKINSONS DISEASE | 2023年 / 13卷 / 02期

关键词：

Caregiver; longitudinal; mood; Parkinson's disease; quality of life; QUALITY-OF-LIFE; BURDEN; SYMPTOMS; THERAPY; SUPPORT;

D O I：

10.3233/JPD-225014

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Background: Although many studies have analyzed what factors contribute to caregiver burden in Parkinson's disease (PD), there is currently no knowledge about how the status of the caregiver could impact the patient. Objective: The aim of this study was to analyze how the change in the caregiver's status influences PD patients. Methods: PD patients and their caregivers who were recruited from January/2016 to November/2017 from 35 centers in Spain from the COPPADIS cohort were included in the study (V0). They were evaluated again at 2-year follow-up (V2). Caregivers completed the Zarit Caregiver Burden Inventory (ZCBI), Caregiver Strain Index (CSI), Beck Depression Inventory-II (BDI-II), and EUROHIS-QOL 8-item index (EUROHIS-QOL8) at V0 and V2. Multivariate models were used to analyze the impact of the change from V0 to V2 ( similar to) on the caregiver's status over the change in the patient's status. Results: similar to BDI-II and similar to EUROHIS-QOL8 in the caregiver predicted similar to BDI-II (similar to = 0.32; p < 0.0001; R2 = 0.71) and similar to EUROHIS-QOL8 (similar to = 0.39; p < 0.0001; R2 = 0.68) in the patient, respectively. Variables related to the caregiver were not associated with changes in the patient ' s health-related QoL ( similar to PDQ-39 [39-item Parkinson's disease Questionnaire]) or autonomy for activities of daily-living ( similar to ADLS [Schwab & England Activities of Daily Living Scale]). Conclusion: The change in the caregiver's mood and global QoL was associated with the change in the patient's mood and global QoL, respectively, independently of other variables of the disease influencing both patient ' s aspects. Based on this finding, it could be of great importance to detect depression in the principal caregiver of a patient and act on it as earlier as possible.

引用

页码：219 / 231

页数：13

共 43 条

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