Effects of mint, menthol, and tobacco-flavored e-cigarettes on tobacco withdrawal symptoms in adults who smoke menthol cigarettes: A laboratory pilot study

被引:2
作者
Bello, Mariel S. [1 ,8 ]
Schulte, Alison R. [2 ]
Ring, Colin R. [3 ]
Cho, Junhan [4 ,5 ]
Barrington-Trimis, Jessica L. - [4 ,5 ]
Pang, Raina D. [4 ,5 ]
Jao, Nancy C. [6 ]
Colby, Suzanne M. [1 ,7 ]
Cassidy, Rachel N. [1 ]
Leventhal, Adam M. [4 ,5 ]
机构
[1] Brown Univ, Sch Publ Hlth, Ctr Alcohol & Addict Studies, Providence, RI USA
[2] Harvard TH Chan Sch Publ Hlth, Dept Global Hlth & Populat, Boston, MA USA
[3] Loma Linda Univ, Dept Psychol, Sch Behav Hlth, Loma Linda, CA USA
[4] Univ Southern Calif, Keck Sch Med, Dept Populat & Publ Hlth Sci, Los Angeles, CA USA
[5] Univ Southern Calif, Inst Addict Sci, Los Angeles, CA USA
[6] Rosalind Franklin Univ Med & Sci, Dept Psychol, N Chicago, IL USA
[7] Brown Univ, Dept Psychiat & Human Behav, Warren Alpert Med Sch, Providence, RI USA
[8] Brown Univ, Ctr Alcohol & Addict Studies CAAS, Sch Publ Hlth, Box G-S121-4, Providence, RI 02912 USA
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
Menthol; Mint flavor; Cigarette smoking; E; -cigarettes; Tobacco withdrawal; Smoking urges; Tobacco abstinence; HIGH-SCHOOL-STUDENTS; UNITED-STATES; NICOTINE; SUBSTITUTION; PATTERNS; MIDDLE; VAPERS; YOUTH;
D O I
10.1016/j.drugalcdep.2024.111110
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
Background: Menthol cigarette smoking has remained stable or increased in certain groups, despite an overall decline in cigarette smoking rates in the U.S. Understanding whether e-cigarettes alter patterns of menthol cigarette use is critical to informing efforts for reducing the public health burden of menthol cigarette smoking. This 2019-2020 laboratory pilot study evaluated whether self-administration of mint-, menthol-, or tobaccoflavored e-cigarettes would differentially impact tobacco withdrawal symptoms in e-cigarette-naive adults who smoke menthol cigarettes daily. Methods: Participants (N=17; 35.3% Female; mean age=51.8) attended three laboratory sessions after 16-hours of tobacco abstinence. Participants self-administered a study-provided JUUL e-cigarette (0.7 mL with 5% nicotine by weight) at each session in which flavor was manipulated (mint vs. menthol vs. tobacco; order randomized). Participants completed pre- and post-e-cigarette administration self-report assessments on smoking urges, nicotine withdrawal, and positive and negative affect states. Multilevel linear regression models tested differences between the three flavor conditions for individual study outcomes. Results: Following overnight tobacco abstinence, vaping either a mint or menthol (vs. tobacco) flavored ecigarette led to significantly greater reductions in smoking urges over time; menthol (vs. tobacco) flavored ecigarettes also suppressed urges to smoke for pleasure. Notably, no differences in nicotine withdrawal, positive affect, or negative affect were observed. Conclusions: In this laboratory pilot study, mint and menthol (vs. tobacco) flavored e-cigarettes provided some negative reinforcement effects via acute reductions in smoking urges during tobacco abstinence, yet only menthol flavored e-cigarettes demonstrated suppressive effects on smoking urges for pleasure in adults who smoke menthol cigarettes daily.
引用
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页数:6
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