Relationship between miRNA-21, miRNA-155, and miRNA-182 expression and inflammatory factors in cerebrospinal fluid from patients with multiple sclerosis

被引：1
|
作者：
Kumar, Neeraj [1 ]
Rauf, Sameer Abdul [1 ]
Riya [2 ]
Arbab, Shahdil [1 ]
机构：
[1] Liaquat Natl Med Coll, Dept Internal Med, Karachi, Pakistan
[2] Dow Med Coll, Dept Internal Med, Karachi, Pakistan
来源：
CLINICAL NEUROLOGY AND NEUROSURGERY | 2024年 / 236卷
关键词：
Multiple sclerosis; Cerebrospinal fluid; Inflammatory factors; Biomarkers; Diagnosis;
D O I：
10.1016/j.clineuro.2023.108054
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
This letter provides insightful perspectives on multiple sclerosis (MS) biomarkers, building upon Behrouz Shademan et al.'s study on miRNA-21, miRNA-155, and miRNA-182 [1]. Beyond these miRNAs, we delve into recent advancements, highlighting promising biomarkers such as ELTD1, CHI3L1, and Fecal Lcn-2. ELTD1 exhibits potential for MS diagnosis, CHI3L1 correlates with disability aspects, and Fecal Lcn-2 serves as a sensitive indicator for gut dysbiosis. Our exploration underscores the evolving landscape of MS biomarker research, urging further investigation for integrating these new markers into diagnostic and monitoring strategies.
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