Paraneoplastic autoimmune limbic encephalitis associated with an atypical carcinoid tumor of the lung

被引:0
作者
Paretas, Emma Marull [1 ]
De Vito, Claudio [4 ]
Catalano, Sabina [1 ]
Vargas, Maria-Isabel [2 ]
Assal, Frederic [1 ]
Lalive, Patrice [1 ,3 ]
Bridel, Claire [1 ]
机构
[1] Geneva Univ Hosp, Fac Med, Dept Neurosci, Div Neurol, Geneva, Switzerland
[2] Geneva Univ Hosp, Dept Radiol, Div Diagnost Neuroradiol, Geneva, Switzerland
[3] Geneva Univ Hosp, Dept Diagnost, Div Lab Med, Geneva, Switzerland
[4] Geneva Univ Hosp, Div Clin Pathol, Geneva, Switzerland
关键词
Cancer; Case report; Cognitive dysfunction; Encephalitis; Magnetic resonance imaging;
D O I
10.1159/000529846
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We report the case of a patient with a history of an atypical lung carcinoid tumor who developed a rapidly progressive memory impairment. The clinical presentation as well as brain MRI, cerebrospinal fluid and laboratory tests led to the diagnosis of seronegative paraneoplastic autoimmune limbic encephalitis. To the best of our knowledge, this is the first case in literature of such association. This case also highlights an exceptionally favorable outcome, both clinically and radiologically, after immunosuppression and tumor removal.
引用
收藏
页码:172 / 176
页数:5
相关论文
共 10 条
  • [1] LIMBIC ENCEPHALITIS AND ITS ASSOCIATION WITH CARCINOMA
    CORSELLIS, JA
    GOLDBERG, GJ
    NORTON, AR
    [J]. BRAIN, 1968, 91 : 481 - +
  • [2] Paraneoplastic limbic encephalitis associated with epidermoid lung carcinoma
    Dabbeche, C
    Guyon, D
    Loubes-Lacroix, F
    Manelfe, C
    [J]. JOURNAL OF NEURORADIOLOGY, 2005, 32 (04) : 278 - 280
  • [3] Paraneoplastic Limbic Encephalitis due to Thymic Carcinoid
    Davis, Melissa
    Ravenel, James G.
    [J]. JOURNAL OF THORACIC ONCOLOGY, 2008, 3 (12) : 1484 - 1486
  • [4] A clinical approach to diagnosis of autoimmune encephalitis
    Graus, Francesc
    Titulaer, Maarten J.
    Balu, Ramani
    Benseler, Susanne
    Bien, Christian G.
    Cellucci, Tania
    Cortese, Irene
    Dale, Russell C.
    Gelfand, Jeffrey M.
    Geschwind, Michael
    Glaser, Carol A.
    Honnorat, Jerome
    Hoeftberger, Romana
    Iizuka, Takahiro
    Irani, Sarosh R.
    Lancaster, Eric
    Leypoldt, Frank
    Pruess, Harald
    Rae-Grant, Alexander
    Reindl, Markus
    Rosenfeld, Myrna R.
    Rostasy, Kevin
    Saiz, Albert
    Venkatesan, Arun
    Vincent, Angela
    Wandinger, Klaus-Peter
    Waters, Patrick
    Dalmau, Josep
    [J]. LANCET NEUROLOGY, 2016, 15 (04) : 391 - 404
  • [5] Anti-Ri antibodies and limbic encephalitis in a patient with carcinoid tumour of the lung
    Harloff, A
    Hummel, S
    Kleinschmidt, M
    Rauer, S
    [J]. JOURNAL OF NEUROLOGY, 2005, 252 (11) : 1404 - 1405
  • [6] Primary Midgut Carcinoid, a Rare Cause of Paraneoplastic Limbic Encephalitis: A Case Report
    Krishnamurthy, Gautham
    Chandramouleeswari, K.
    Bose, Jagadeesh Chandra
    Rajendran
    [J]. JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2014, 8 (02) : 157 - 158
  • [7] Paraneoplastic Limbic Encephalitis in a Male with Squamous Cell Carcinoma of the Lung
    Sauri, Tamara
    Izquierdo, Angel
    Ramio-Torrenta, Lluis
    Sanchez-Montanez, Angel
    Bosch-Barrera, Joaquim
    Porta, Rut
    [J]. JOURNAL OF CLINICAL NEUROLOGY, 2015, 11 (01): : 87 - 91
  • [8] Long-term survival and recurrence after resection of bronchopulmonary carcinoids: A single-center cohort study of 236 patients
    Soldath, Patrick
    Binderup, Tina
    Kjaer, Andreas
    Federspiel, Birgitte
    Langer, Seppo W.
    Knigge, Ulrich
    Petersen, Rene Horsleben
    [J]. LUNG CANCER, 2021, 156 : 109 - 116
  • [9] WHO Classification of Tumors, 2021, THOR TUM, V5th
  • [10] Evaluation of the Prognostic Significance of TNM Staging Guidelines in Lung Carcinoid Tumors
    Yoon, Ji Yoon
    Sigel, Keith
    Martin, Jacob
    Jordan, Robyn
    Beasley, Mary Beth
    Smith, Cardinale
    Kaufman, Andrew
    Wisnivesky, Juan
    Kim, Michelle Kang
    [J]. JOURNAL OF THORACIC ONCOLOGY, 2019, 14 (02) : 184 - 192