A Critical Review On Nanotechnology: A Technique in Cancer Detection and Prophylaxis

被引:2
作者
Bharadwaj, Alok [1 ]
Gupta, Mansi [1 ]
Shakya, Akankasha [1 ]
机构
[1] GLA Univ, Dept Biotechnol, Mathura, Uttar Pradesh, India
关键词
Nanotechnology; cancer detection; prophylaxis; cancer biomarkers; TISSUE-PLASMINOGEN ACTIVATOR; SOLID LIPID NANOPARTICLES; TARGETED DRUG-DELIVERY; QUANTUM DOTS; IN-VITRO; SILICA-NANOPARTICLES; THERANOSTIC NANOMEDICINE; POLYMERIC NANOPARTICLES; GREEN SYNTHESIS; DOXORUBICIN;
D O I
10.1142/S1793984423300042
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
In the present scenario, cancer is found to be one of the distressing diseases that accounts for huge number of deaths all around the world. Till now, several conventional treatments like radiation therapy, chemotherapy and immunotherapy were available but due to certain restrictions like scarcity of specificity, cytotoxicity and multi-drug resistance which were the major issues that pose the hurdle in successful cancer treatment. Owing the presence of toxicity and resistance to immunity with traditional treatment procedures, some effective technology like nanotechnology is being used to efficiently treat the cancer and reduce the chances of risk. In the past, nanotechnology-based immunotherapeutic agents have been employed to treat cancerous cells by separating normal cells from the target site. With this special feature, nanotechnology might be the ray of hope for rapid, cheap and secured technique for the identification and treatment of cancer cells and cancer biomarkers. This technique involves certain nanomaterials like carbon nanotubes, liposomes and polymeric micelles that help in the formulation of cancer drugs that have been found to have a significant pharmacokinetic and pharmacodynamic application in the diagnosis and prophylaxis of cancer. In this review, our prime focus is on the utility of nanoparticles (NPs) in cancer diagnosis and prophylaxis. Apart from this, we also discuss about the challenges that hamper the utility of NPs and also give suitable remedial approaches for the same.
引用
收藏
页数:14
相关论文
共 155 条
[1]   Antibody-drug nanoparticle induces synergistic treatment efficacies in HER2 positive breast cancer cells [J].
Abedin, Muhammad Raisul ;
Powers, Kaitlyne ;
Aiardo, Rachel ;
Barua, Dibbya ;
Barua, Sutapa .
SCIENTIFIC REPORTS, 2021, 11 (01)
[2]   Ovarian cancer: Strategies for overcoming resistance to chemotherapy [J].
Agarwal, R ;
Kaye, SB .
NATURE REVIEWS CANCER, 2003, 3 (07) :502-516
[3]  
Aghebati-Maleki A., 2020, J CELL PHYSL, V235
[4]   Targeting cancer cells with nanotherapeutics and nanodiagnostics: Current status and future perspectives [J].
Ali, Eunus S. ;
Sharker, Shazid Md ;
Islam, Muhammad Torequl ;
Khan, Ishaq N. ;
Shaw, Subrata ;
Rahman, Md Atiqur ;
Uddin, Shaikh Jamal ;
Shill, Manik Chandra ;
Rehman, Shahnawaz ;
Das, Niranjan ;
Ahmad, Saheem ;
Shilpi, Jamil A. ;
Tripathi, Swati ;
Mishra, Siddhartha Kumar ;
Mubarak, Mohammad S. .
SEMINARS IN CANCER BIOLOGY, 2021, 69 :52-68
[5]   Green synthesis of zinc sulfide (ZnS) nanoparticles using Stevia rebaudiana Bertoni and evaluation of its cytotoxic properties [J].
Alijani, Hajar Q. ;
Pourseyedi, Shahram ;
Mahani, Masoud Torkzadeh ;
Khatami, Mehrdad .
JOURNAL OF MOLECULAR STRUCTURE, 2019, 1175 :214-218
[6]  
Allen JD, 2000, CANCER RES, V60, P5761
[7]   Liposomal drug delivery systems: From concept to clinical applications [J].
Allen, Theresa M. ;
Cullis, Pieter R. .
ADVANCED DRUG DELIVERY REVIEWS, 2013, 65 (01) :36-48
[8]   Recent Advances in Nanoparticle-Based Cancer Drug and Gene Delivery [J].
Amreddy, Narsireddy ;
Babu, Anish ;
Muralidharan, Ranganayaki ;
Panneerselvam, Janani ;
Srivastava, Akhil ;
Ahmed, Rebaz ;
Mehta, Meghna ;
Munshi, Anupama ;
Ramesh, Rajagopal .
ADVANCES IN CANCER RESEARCH, VOL 137, 2018, 137 :115-170
[9]  
Ansari KA, 2011, CURR DRUG DELIV, V8, P194
[10]  
Asadian E., 2019, SENS ACTUATORS B, V183, P1