Transition metal complexes with tetradentate Schiff bases (N2O2) obtained from salicylaldehyde: A review of their possible anticancer properties

被引：37

作者：

Alfonso-Herrera, Luis A. ^{[1
,2
]}

Hernandez-Romero, Delia ^{[1
]}

Cruz-Navarro, J. Antonio ^{[1
,3
]}

Ramos-Ligonio, Angel ^{[1
]}

Lopez-Monteon, Aracely ^{[1
]}

Rivera-Villanueva, Jose M. ^{[1
]}

Morales-Morales, David ^{[3
]}

Colorado-Peralta, Raul ^{[1
]}

机构：

[1] Univ Veracruzana, Fac Ciencias Quim, Prolongac Oriente 6,1009, Orizaba 94340, Veracruz, Mexico

[2] Univ Autonoma Metropolitana Azcapotzalco, Dept Ciencias Basicas, Ave San Pablo,180, Mexico City 02200, Mexico

[3] Univ Nacl Autonoma Mexico, Inst Quim, Circuito Exterior S-N, Mexico City 04510, Mexico

来源：

COORDINATION CHEMISTRY REVIEWS | 2024年 / 505卷

关键词：

G-QUADRUPLEX DNA; VERSATILE BUILDING-BLOCKS; IN-VITRO CYTOTOXICITY; BOVINE SERUM-ALBUMIN; KETO-ENOL ISOMERISM; SALEN COMPLEXES; CRYSTAL-STRUCTURE; SALPHEN COMPLEXES; MOLECULAR DOCKING; PROTEIN-BINDING;

D O I：

10.1016/j.ccr.2024.215698

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Despite multiple advances in prevention and treatment, cancer remains a deadly disease globally. From 1942 to the present day, chemotherapy has been recognized as one of the main alternatives in the treatment of cancer. Nevertheless, the use of anticancer metallodrugs was investigated until 1965, when the therapeutic application of cisplatin was discovered circumstantially. Currently, other metallodrugs based on platinum and ruthenium have reached intermediate and advanced clinical research phases, some even reaching the market (carboplatin, heptaplatin, lobaplatin, miriplatin, nedaplatin, oxaliplatin, etc.). During the last decades, scientists have developed new metallodrugs that are more effective and selective, but with fewer side effects. Metal complexes based on transition metals have demonstrated very good anticancer activity, mainly when coordinated with organic ligands containing nitrogen or oxygen. In this sense, various reports have confirmed that Schiff bases derived from salicylaldehyde form ideal N2O2 ligands (salphen, salen, salpn) to design coordination complexes with dblock metals potentially useful in chemotherapy. Therefore, this document could pave the way for the scientific community focused on the design of new metallodrugs based on tetradentate Schiff bases and transition metals.

引用

页数：43

共 255 条

[11] Enhanced G-Quadruplex DNA Stabilization and Telomerase Inhibition by Novel Fluorescein Derived Salen and Salphen Based Ni(II) and Pd(II) Complexes [J].

Ali, Asfa ;

Kamra, Mohini ;

Roy, Soma ;

Muniyappa, K. ;

Bhattacharya, Santanu .

BIOCONJUGATE CHEMISTRY, 2017, 28 (02) :341-352

[12] Novel Oligopyrrole Carboxamide based Nickel(II) and Palladium(II) Salens, Their Targeting of Human G-Quadruplex DNA, and Selective Cancer Cell Toxicity [J].

Ali, Asfa ;

Kamra, Mohini ;

Roy, Soma ;

Muniyappa, K. ;

Bhattacharya, Santanu .

CHEMISTRY-AN ASIAN JOURNAL, 2016, 11 (18) :2542-2554

[13] New Fe(III) and Co(II) salen complexes with pendant distamycins: selective targeting of cancer cells by DNA damage and mitochondrial pathways [J].

Ali, Asfa ;

Kamra, Mohini ;

Bhan, Arunoday ;

Mandal, Subhrangsu S. ;

Bhattacharya, Santanu .

DALTON TRANSACTIONS, 2016, 45 (22) :9345-9353

[14] Biomolecular Interaction, Anti-Cancer and Anti-Angiogenic Properties of Cobalt(III) Schiff Base Complexes [J].

Ambika, Subramanian ;

Manojkumar, Yesaiyan ;

Arunachalam, Sankaralingam ;

Gowdhami, Balakrishnan ;

Sundaram, Kishore Kumar Meenakshi ;

Solomon, Rajadurai Vijay ;

Venuvanalingam, Ponnambalam ;

Akbarshaz, Mohammad Abdulkader ;

Sundararaman, Muthuraman .

SCIENTIFIC REPORTS, 2019, 9 (1)

[15] Antioxidant, Antibacterial, and Anti-diabetic Activity of Green Synthesized Copper Nanoparticles of Cocculus hirsutus (Menispermaceae) [J].

Ameena, Shaik ;

Rajesh, Nambi ;

Anjum, Syeda M. ;

Khadri, Habeeb ;

Riazunnisa, Khateef ;

Mohammed, Arifullah ;

Kari, Zulhisyam Abdul .

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2022, 194 (10) :4424-4438

[16] Metal ions in biological catalysis: from enzyme databases to general principles [J].

Andreini, Claudia ;

Bertini, Ivano ;

Cavallaro, Gabriele ;

Holliday, Gemma L. ;

Thornton, Janet M. .

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2008, 13 (08) :1205-1218

[17] Compartmental Schiff-base ligands-a rich library of tectons in designing magnetic and luminescent materials [J].

Andruh, Marius .

CHEMICAL COMMUNICATIONS, 2011, 47 (11) :3025-3042

[18] Fe(III)-Salen and Salphen Complexes Induce Caspase Activation and Apoptosis in Human Cells [J].

Ansari, Khairul I. ;

Kasiri, Sahba ;

Grant, James D. ;

Mandal, Subhrangsu S. .

JOURNAL OF BIOMOLECULAR SCREENING, 2011, 16 (01) :26-35

[19] Apoptosis and anti-tumour activities of manganese(III)-salen and -salphen complexes [J].

Ansari, Khairul I. ;

Kasiri, Sahba ;

Grant, James D. ;

Mandal, Subhrangsu S. .

DALTON TRANSACTIONS, 2009, (40) :8525-8531

[20] Manganese(III)-salens induce tumor selective apoptosis in human cells [J].

Ansari, Khairul I. ;

Grant, James D. ;

Kasiri, Sahba ;

Woldemariam, Getachew ;

Shrestha, Bishakha ;

Mandal, Subhrangsu S. .

JOURNAL OF INORGANIC BIOCHEMISTRY, 2009, 103 (05) :818-826

← 1 2 3 4 5 6 7 8 9 10 →