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Unmasking bipolarity in recurrent depressive disorder following herpes simplex virus triggered n-methyl-D-aspartate encephalitis
被引:8
|作者:
Narasimhappa, Karthik
[1
]
Mamtani, Harkishan
[1
]
Jain, Kshiteeja
[2
]
Holla, Vikram V.
[2
]
Ganjekar, Sundarnag
[1
]
Manjunath, Netravathi
[2
]
Kulanthaivelu, Karthik
[3
]
Desai, Geetha
[1
]
机构:
[1] Natl Inst Mental Hlth & Neuro Sci NIMHANS, Dept Psychiat, Hosur Rd, Bangalore 560029, India
[2] Natl Inst Mental Hlth & Neuro Sci NIMHANS, Dept Neurol, Bangalore, India
[3] Natl Inst Mental Hlth & Neuro Sci NIMHANS, Dept Neuro Imaging & Intervent Radiol, Bangalore, India
关键词:
bipolarity;
herpes simplex encephalitis;
NMDA encephalitis;
recurrent depression;
D O I:
10.1111/bdi.13393
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
ObjectiveHerpes simplex virus (HSV) infection triggered n-methyl-D-aspartate (NMDA) encephalitis can lead to varied neuropsychiatric manifestations, including movement disorders and manic symptoms. HSV is known to affect the same brain regions as in secondary mania.MethodWe present a 35-year-old female diagnosed with recurrent depressive disorder (RDD) who developed NMDA encephalitis triggered by HSV infection.ResultHSV-triggered NMDA encephalitis led to a manic switch in a woman with RDD on antidepressants, along with the new onset of dyskinetic movements.ConclusionA neurological insult predisposed our patient to the variable effects of antidepressant drugs.
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页码:192 / 195
页数:4
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