Unmasking bipolarity in recurrent depressive disorder following herpes simplex virus triggered n-methyl-D-aspartate encephalitis

被引:8
|
作者
Narasimhappa, Karthik [1 ]
Mamtani, Harkishan [1 ]
Jain, Kshiteeja [2 ]
Holla, Vikram V. [2 ]
Ganjekar, Sundarnag [1 ]
Manjunath, Netravathi [2 ]
Kulanthaivelu, Karthik [3 ]
Desai, Geetha [1 ]
机构
[1] Natl Inst Mental Hlth & Neuro Sci NIMHANS, Dept Psychiat, Hosur Rd, Bangalore 560029, India
[2] Natl Inst Mental Hlth & Neuro Sci NIMHANS, Dept Neurol, Bangalore, India
[3] Natl Inst Mental Hlth & Neuro Sci NIMHANS, Dept Neuro Imaging & Intervent Radiol, Bangalore, India
关键词
bipolarity; herpes simplex encephalitis; NMDA encephalitis; recurrent depression;
D O I
10.1111/bdi.13393
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
ObjectiveHerpes simplex virus (HSV) infection triggered n-methyl-D-aspartate (NMDA) encephalitis can lead to varied neuropsychiatric manifestations, including movement disorders and manic symptoms. HSV is known to affect the same brain regions as in secondary mania.MethodWe present a 35-year-old female diagnosed with recurrent depressive disorder (RDD) who developed NMDA encephalitis triggered by HSV infection.ResultHSV-triggered NMDA encephalitis led to a manic switch in a woman with RDD on antidepressants, along with the new onset of dyskinetic movements.ConclusionA neurological insult predisposed our patient to the variable effects of antidepressant drugs.
引用
收藏
页码:192 / 195
页数:4
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