The impact of thromboelastography on patients with penetrating abdominal trauma requiring intensive care

被引:0
作者
Hannington, M. [1 ]
Nel, D. [1 ]
Miller, M. [1 ,2 ]
Nicol, A. [1 ]
Navsaria, P. [1 ,3 ]
机构
[1] Univ Cape Town, Groote Schuur Hosp, Dept Gen Surg, Cape Town, South Africa
[2] Univ Cape Town, Groote Schuur Hosp, Dept Crit Care, Cape Town, South Africa
[3] Univ Cape Town, Groote Schuur Hosp, Trauma Surg, Cape Town, South Africa
关键词
thromboelastography; penetrating abdominal trauma; critical care; FIBRINOLYSIS SHUTDOWN; DAMAGE CONTROL; COAGULOPATHY; MORTALITY; THROMBELASTOGRAPHY; HYPOCOAGULABILITY; TRANSFUSION; HYPOTHERMIA; ACIDOSIS; INJURY;
D O I
10.36303/SAJS.3950
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: Trauma-induced coagulopathy (TIC) is a complex multifaceted process which contributes to higher mortality rates in severely injured trauma patients. Thromboelastography (TEG) is effective in detecting TIC which assists in instituting goal-directed therapy as part of damage control resuscitation.Methods: This retrospective study included all adult patients over a 36-month period with penetrating abdominal trauma who required a laparotomy, blood products and admission for critical care. Analysis included demographics, admission data, 24-hour interventions, TEG parameters and 30-day outcomes.Results: Eighty-four patients with a median age of 28 years were included. The majority (93%; 78/84) suffered from a gunshot injury, with 75% (63/84) receiving a damage control laparotomy. Forty-eight patients (57%) had a TEG. Injury severity score and total fluid and blood product administered in the first 24 hours were all significantly higher in patients who had a TEG (p < 0.05). TEG profiles were: 42% (20/48) normal, 42% (20/48) hypocoagulable, 12% (6/48) hypercoagulable and 4% (2/48) mixed parameters. Fibrinolysis profiles were: 48% (23/48) normal, 44% (21/48) fibrinolysis shutdown and 8% (4/48) hyperfibrinolysis. Mortality rate was 5% (4/84) at 24 hours and 26% (22/84) at 30 days, with no difference between the two groups. High-grade complication rates, days on a ventilator and intensive care unit length of stay were all significantly higher in patients who did not have a TEG.Conclusion: TIC is common in severely injured penetrating trauma patients. The usage of a thromboelastogram did not impact on 24-hour or 30-day mortality but did result in a decreased intensive care stay and a decreased high-grade
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页码:133 / 138
页数:6
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共 26 条
  • [1] Open abdomen in the trauma ICU patient: who? when? why? and what are the outcome results?
    Boolaky, Kurt Nirishan
    Tariq, Ali Hassan
    Hardcastle, Timothy Craig
    [J]. EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY, 2022, 48 (02) : 953 - 961
  • [2] THROMBOELASTOGRAM EVALUATION OF THE IMPACT OF HYPERCOAGULABILITY IN TRAUMA PATIENTS
    Branco, Bernardino C.
    Inaba, Kenji
    Ives, Crystal
    Okoye, Obi
    Shulman, Ira
    David, Jean-Stephane
    Schoechl, Herbert
    Rhee, Peter
    Demetriades, Demetrios
    [J]. SHOCK, 2014, 41 (03): : 200 - 207
  • [3] The Clavien-Dindo Classification of Surgical Complications Five-Year Experience
    Clavien, Pierre A.
    Barkun, Jeffrey
    de Oliveira, Michelle L.
    Vauthey, Jean Nicolas
    Dindo, Daniel
    Schulick, Richard D.
    de Santibanes, Eduardo
    Pekolj, Juan
    Slankamenac, Ksenija
    Bassi, Claudio
    Graf, Rolf
    Vonlanthen, Rene
    Padbury, Robert
    Cameron, John L.
    Makuuchi, Masatoshi
    [J]. ANNALS OF SURGERY, 2009, 250 (02) : 187 - 196
  • [4] Effect of thromboelastography (TEG®) and rotational thromboelastometry (ROTEM®) on diagnosis of coagulopathy, transfusion guidance and mortality in trauma: descriptive systematic review
    Da Luz, Luis Teodoro
    Nascimento, Bartolomeu
    Shankarakutty, Ajith Kumar
    Rizoli, Sandro
    Adhikari, Neill K. J.
    [J]. CRITICAL CARE, 2014, 18 (05)
  • [5] Modern Management of Bleeding, Clotting, and Coagulopathy in Trauma Patients: What Is the Role of Viscoelastic Assays?
    Dhara, Sanjeev
    Moore, Ernest E.
    Yaffe, Michael B.
    Moore, Hunter B.
    Barrett, Christopher D.
    [J]. CURRENT TRAUMA REPORTS, 2020, 6 (01) : 69 - 81
  • [6] Goal-directed Hemostatic Resuscitation of Trauma-induced Coagulopathy A Pragmatic Randomized Clinical Trial Comparing a Viscoelastic Assay to Conventional Coagulation Assays
    Gonzalez, Eduardo
    Moore, Ernest E.
    Moore, Hunter B.
    Chapman, Michael P.
    Chin, Theresa L.
    Ghasabyan, Arsen
    Wohlauer, Max V.
    Barnett, Carlton C.
    Bensard, Denis D.
    Biffl, Walter L.
    Burlew, Clay C.
    Johnson, Jeffrey L.
    Pieracci, Fredric M.
    Jurkovich, Gregory J.
    Banerjee, Anirban
    Silliman, Christopher C.
    Sauaia, Angela
    [J]. ANNALS OF SURGERY, 2016, 263 (06) : 1051 - 1059
  • [7] Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma The PROPPR Randomized Clinical Trial
    Holcomb, John B.
    Tilley, Barbara C.
    Baraniuk, Sarah
    Fox, Erin E.
    Wade, Charles E.
    Podbielski, Jeanette M.
    del Junco, Deborah J.
    Brasel, Karen J.
    Bulger, Eileen M.
    Callcut, Rachael A.
    Cohen, Mitchell Jay
    Cotton, Bryan A.
    Fabian, Timothy C.
    Inaba, Kenji
    Kerby, Jeffrey D.
    Muskat, Peter
    O'Keeffe, Terence
    Rizoli, Sandro
    Robinson, Bryce R. H.
    Scalea, Thomas M.
    Schreiber, Martin A.
    Stein, Deborah M.
    Weinberg, Jordan A.
    Callum, Jeannie L.
    Hess, John R.
    Matijevic, Nena
    Miller, Christopher N.
    Pittet, Jean-Francois
    Hoyt, David B.
    Pearson, Gail D.
    Leroux, Brian
    van Belle, Gerald
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2015, 313 (05): : 471 - 482
  • [8] Hypocoagulability, as evaluated by thrombelastography, at admission to the ICU is associated with increased 30-day mortality
    Johansson, Par I.
    Stensballe, Jakob
    Vindelov, Nis
    Perner, Anders
    Espersen, Kurt
    [J]. BLOOD COAGULATION & FIBRINOLYSIS, 2010, 21 (02) : 168 - 174
  • [9] Primary Fibrinolysis Is Integral in the Pathogenesis of the Acute Coagulopathy of Trauma
    Kashuk, Jeffry L.
    Moore, Ernest E.
    Sawyer, Michael
    Wohlauer, Max
    Pezold, Michael
    Barnett, Carlton
    Biffl, Walter L.
    Burlew, Clay C.
    Johnson, Jeffrey L.
    Sauaia, Angela
    [J]. ANNALS OF SURGERY, 2010, 252 (03) : 434 - 444
  • [10] Trauma-induced coagulopathy: The past, present, and future
    Kornblith, Lucy Z.
    Moore, Hunter B.
    Cohen, Mitchell J.
    [J]. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2019, 17 (06) : 852 - 862