Liquid biopsy: from concept to clinical application

被引：36

作者：

Alix-Panabieres, Catherine ^{[1
,2
,3
,8
]}

Marchetti, Dario ^{[4
,5
]}

Lang, Julie E. ^{[6
,7
]}

机构：

[1] Univ Med Ctr Montpellier, Lab Rare Circulating Human Cells LCCRH, Montpellier, France

[2] Univ Montpellier, CNRS, CREEC CANECEV, MIVEGEC CREES,IRD, Montpellier, France

[3] European Liquid Biopsy Soc ELBS, Hamburg, Germany

[4] Univ New Mexico, Dept Internal Med, Hlth Sci Ctr, MSC07 4025,1 Univ New Mexico, Albuquerque, NM 87131 USA

[5] Univ New Mexico, Dept Pathol, Hlth Sci Ctr, UNM Comprehens Canc Ctr, MSC07 4025,1 Univ New Mexico, Albuquerque, NM 87131 USA

[6] Cleveland Clin, Breast Surg & Canc Biol, 9500 Euclid Ave,A80, Cleveland, OH USA

[7] Cleveland Clin, Case Comprehens Canc Ctr, 9500 Euclid Ave,A80, Cleveland, OH USA

[8] Inst Univ Rech Clin IURC, 641 Ave Doyen Gaston Giraud, F-34093 Montpellier 5, France

来源：

SCIENTIFIC REPORTS | 2023年 / 13卷 / 01期

关键词：

CIRCULATING TUMOR-CELLS; BREAST-CANCER; DNA;

D O I：

10.1038/s41598-023-48501-x

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The diagnosis and treatment of cancer presents a physical and mental burden to the patient, often involving diagnostic biopsies and surgeries or chemotherapeutic approaches with severe side-effects. Advances which enable early detection of cancer and close monitoring of the disease course without invasive procedures, and which can underpin a tailored approach to treatment, can therefore make a big difference to the quality of life of patients. Liquid biopsies can be used to access tumor cells and tumor DNA circulating in the blood. Monitoring these species can provide a minimally invasive and repeatable means to detect cancer, or gain information about its response to treatment.

引用

页数：4

共 28 条

[1] Liquid Biopsy: From Discovery to Clinical Application [J].

Alix-Panabieres, Catherine ;

Pantel, Klaus .

CANCER DISCOVERY, 2021, 11 (04) :858-873

[2] Perspective: The future of liquid biopsy [J].

Alix-Panabieres, Catherine .

NATURE, 2020, 579 (7800) :S9-S9

[3] Genetic analysis of heterogeneous subsets of circulating tumour cells from high grade serous ovarian carcinoma patients [J].

Asante, Du-Bois ;

Mohan, Ganendra R. K. A. ;

Acheampong, Emmanuel ;

Ziman, Melanie ;

Calapre, Leslie ;

Meniawy, Tarek M. ;

Gray, Elin S. ;

Beasley, Aaron B. .

SCIENTIFIC REPORTS, 2023, 13 (01)

[4]

Bao-Caamano A, 2023, SCI REP-UK, V13, DOI 10.1038/s41598-023-42037-w

[5] Properties of non-coding mutation hotspots as urinary biomarkers for bladder cancer detection [J].

Baxter, L. ;

Gordon, N. S. ;

Ott, S. ;

Wang, J. ;

Patel, P. ;

Goel, A. ;

Piechocki, K. ;

Silcock, L. ;

Sale, C. ;

Zeegers, M. P. ;

Cheng, K. K. ;

James, N. D. ;

BladderPath Trial Management Grp, A. ;

Knight, A. ;

Gallagher, J. ;

Magwaro, S. ;

Hughes, A. ;

Pope, A. ;

Tunariu, N. ;

Doyle, H. ;

Liu, W. ;

Mintz, H. ;

Nanton, V. ;

James, K. ;

Hafeez, S. ;

Catto, J. W. F. ;

Jefferson, K. ;

Pirrie, S. J. ;

Bryan, R. T. ;

Ward, D. G. .

SCIENTIFIC REPORTS, 2023, 13 (01)

[6] Identification of TP53 mutations in circulating tumour DNA in high grade serous ovarian carcinoma using next generation sequencing technologies [J].

Calapre, Leslie ;

Giardina, Tindaro ;

Beasley, Aaron B. B. ;

Reid, Anna L. L. ;

Stewart, Colin ;

Amanuel, Benhur ;

Meniawy, Tarek M. M. ;

Gray, Elin S. S. .

SCIENTIFIC REPORTS, 2023, 13 (01)

[7] Personalized Detection of Circulating Tumor DNA Antedates Breast Cancer Metastatic Recurrence [J].

Coombes, Raoul Charles ;

Page, Karen ;

Salari, Raheleh ;

Hastings, Robert K. ;

Armstrong, Anne ;

Ahmed, Samreen ;

Ali, Simak ;

Cleator, Susan ;

Kenny, Laura ;

Stebbing, Justin ;

Rutherford, Mark ;

Sethi, Himanshu ;

Boydell, Anna ;

Swenerton, Ryan ;

Fernandez-Garcia, Daniel ;

Gleason, Kelly L. T. ;

Goddard, Katie ;

Guttery, David S. ;

Assaf, Zoe J. ;

Wu, Hsin-Ta ;

Natarajan, Prashanthi ;

Moore, David A. ;

Primrose, Lindsay ;

Dashner, Scott ;

Tin, Antony S. ;

Balcioglu, Mustafa ;

Srinivasan, Ramya ;

Shchegrova, Svetlana V. ;

Olson, Alexander ;

Hafez, Dina ;

Billings, Paul ;

Aleshin, Alexey ;

Rehman, Farah ;

Toghill, Bradley J. ;

Hills, Allison ;

Louie, Maggie C. ;

Lin, Cheng-Ho Jimmy ;

Zimmermann, Bernhard G. ;

Shaw, Jaqueline A. .

CLINICAL CANCER RESEARCH, 2019, 25 (14) :4255-4263

[8] Circulating tumor cells, disease progression, and survival in metastatic breast cancer [J].

Cristofanilli, M ;

Budd, GT ;

Ellis, MJ ;

Stopeck, A ;

Matera, J ;

Miller, MC ;

Reuben, JM ;

Doyle, GV ;

Allard, WJ ;

Terstappen, LWMM ;

Hayes, DF .

NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (08) :781-791

[9] Precision cancer medicine: Concepts, current practice, and future developments [J].

Edsjo, Anders ;

Holmquist, Louise ;

Geoerger, Birgit ;

Nowak, Frederique ;

Gomon, Georgy ;

Alix-Panabieres, Catherine ;

Ploeger, Carolin ;

Lassen, Ulrik ;

Le Tourneau, Christophe ;

Lehtio, Janne ;

Ott, Patrick A. ;

von Deimling, Andreas ;

Froehling, Stefan ;

Voest, Emile ;

Klauschen, Frederick ;

Dienstmann, Rodrigo ;

Alshibany, Aisha ;

Siu, Lillian L. ;

Stenzinger, Albrecht .

JOURNAL OF INTERNAL MEDICINE, 2023, 294 (04) :455-481

[10] Circulating cf-miRNA as a more appropriate surrogate liquid biopsy marker than cfDNA for ovarian cancer [J].

Gahlawat, Aoife Ward ;

Witte, Tania ;

Sinn, Peter ;

Schott, Sarah .

SCIENTIFIC REPORTS, 2023, 13 (01)

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