Advances in the management of type 2 diabetes in adults

被引：26

作者：

Galindo, Rodolfo J. ^{[1
,2
]}

Trujillo, Jennifer M. ^{[3
]}

Wang, Cecilia C. Low ^{[4
]}

McCoy, Rozalina G. ^{[5
,6
]}

机构：

[1] Univ Miami, Miller Sch Med, Div Endocrinol Diabet & Metab, Miami, FL USA

[2] Univ Miami, Miller Sch Med, Diabet Res Inst, Miami, FL USA

[3] Univ Colorado, Skaggs Sch Pharm & Pharmaceut Sci, Dept Clin Pharm, Anschutz Med Campus, Aurora, CO 80045 USA

[4] Univ Colorado, Div Endocrinol Metab & Diabet, Sch Med, Anschutz Med Campus, Aurora, CO USA

[5] Univ Maryland, Sch Med, Dept Med, Div Endocrinol Diabet & Nutr, Baltimore, MD 21201 USA

[6] Univ Maryland, Inst Hlth Comp, Bethesda, MD USA

来源：

BMJ MEDICINE | 2023年 / 2卷 / 01期

基金：

美国国家卫生研究院;

关键词：

Diabetes mellitus; Ambulatory care; Endocrinology; Internal medicine; Metabolic diseases; Primary health care; LIFE-STYLE INTERVENTION; CARDIOVASCULAR RISK-FACTORS; INTENSIVE GLUCOSE CONTROL; ADVANCED LIVER FIBROSIS; WEIGHT-LOSS; SEVERE HYPOGLYCEMIA; BARIATRIC SURGERY; GLYCEMIC CONTROL; UNITED-STATES; ETHNIC-DIFFERENCES;

D O I：

10.1136/bmjmed-2022-000372

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Type 2 diabetes is a chronic and progressive cardiometabolic disorder that affects more than 10% of adults worldwide and is a major cause of morbidity, mortality, disability, and high costs. Over the past decade, the pattern of management of diabetes has shifted from a predominantly glucose centric approach, focused on lowering levels of haemoglobin A1c (HbA1c), to a directed complications centric approach, aimed at preventing short term and long term complications of diabetes, and a pathogenesis centric approach, which looks at the underlying metabolic dysfunction of excess adiposity that both causes and complicates the management of diabetes. In this review, we discuss the latest advances in patient centred care for type 2 diabetes, focusing on drug and non-drug approaches to reducing the risks of complications of diabetes in adults. We also discuss the effects of social determinants of health on the management of diabetes, particularly as they affect the treatment of hyperglycaemia in type 2 diabetes.

引用

页数：16

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