Myasthenia gravis: Frequently asked questions

被引:13
作者
Morren, John A. [1 ,2 ]
Li, Yuebing [2 ,3 ,4 ]
机构
[1] Cleveland Clin, Neurol Inst, Neuromuscular Ctr, Cleveland, OH USA
[2] Case Western Reserve Univ, Cleveland Clin Lerner Coll Med, Cleveland, OH USA
[3] Cleveland Clin, Neurol Inst, Neuromuscular Ctr, Dept Neurol, Cleveland, OH USA
[4] Cleveland Clin, Neurol Inst, S90,9500 Euclid Ave, Cleveland, OH 44195 USA
关键词
INTERNATIONAL CONSENSUS GUIDANCE; QUALITY-OF-LIFE; DOUBLE-BLIND; THYMECTOMY; PREDNISONE; MANAGEMENT;
D O I
10.3949/ccjm.90a.22017
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Myasthenia gravis is a disorder of neuromuscular junction transmission, the result of antibodies against the post synaptic aspect of the neuromuscular junction. Its clinical hallmark is fatigable weakness of skeletal muscles, which tends to vary in location and severity among patients. It is treated with pyridostigmine, immunotherapy, and thymectomy. Treatment is often individualized according to disease severity, antibody status, comorbidities, and other factors. This review uses a question-and-answer format to provide up-to-date, high-yield, clinically relevant information on myasthenia gravis.
引用
收藏
页码:103 / 113
页数:11
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