Efficacy of a New Hemostatic Dental Sponge in Controlling Bleeding, Pain, and Dry Socket Following Mandibular Posterior Teeth Extraction-A Split-Mouth Randomized Double-Blind Clinical Trial

被引:6
作者
Mahmoudi, Armin [1 ]
Ghavimi, Mohammad Ali [1 ]
Maleki Dizaj, Solmaz [2 ,3 ]
Sharifi, Simin [2 ]
Sajjadi, Seyyede Shabnam [4 ]
Jamei Khosroshahi, Amir Reza [4 ]
机构
[1] Tabriz Univ Med Sci, Fac Dent, Dept Oral & Maxillofacial Surg, Tabriz 5154853431, Iran
[2] Tabriz Univ Med Sci, Dent & Periodontal Res Ctr, Tabriz 5154853431, Iran
[3] Tabriz Univ Med Sci, Fac Dent, Dept Dent Biomat, Tabriz 5154853431, Iran
[4] Tabriz Univ Med Sci, Fac Dent, Dept Pediat Dent, Tabriz 5154853431, Iran
关键词
gelatin; sponge; hemostatic; pain; dry socket; randomized; double-blind; split-mouth; 3RD MOLAR; PREVENTION;
D O I
10.3390/jcm12144578
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aims: This study aimed to clinically evaluate of a novel gelatin-based biodegradable sponge after mandibular posterior teeth extraction to assess its abilities in controlling bleeding, pain, and dry socket compared a commercial sponge. Trial design: In this study, 26 patients who needed the extraction of two mandibular molar teeth were selected and, in each patient, after tooth extraction, the prepared gelatin sponge was used in the test group and the commercial sponge was used in the control group in the form of a randomized, double-blind, split-mouth clinical trial. The sterile gauzes were used on top of each sponge to absorb the extra blood (unabsorbed blood of sponges) to assess the blood absorption amount. Also, the amount of bleeding was recorded for 1 and 4 h after extraction for two groups. The amount of pain was measured for 12, 24, and 48 h after tooth extraction by Visual Analogue Scale (VAS). All patients also returned for examination four days after extraction to assess the occurrence of dry socket. Results: The results showed that the average weight of absorbed blood by sterile gauze in the control group (6.32 & PLUSMN; 1.06 g) was higher than in test group (3.97 & PLUSMN; 1.1 g), e.g., the bleeding control was better for the test group (p < 0.05). Bleeding was observed to be significantly reduced in the test group within 1 h (p = 0.003), within 1-4 h (p = 0.002), and after 4 h (p = 0.042) post-operatively in comparison to the control group. The average pain decreased significantly over time in both groups and the reduction of the pain was significantly higher for the test group (p < 0.05). Just one dry socket case occurred in the control group. Conclusion: The prepared sponge is recommended for use in dental surgeries because of its abilities in bleeding, pain, and dry socket control.
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页数:11
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