Serum iron and ferritin levels in female patients with gingivitis and periodontitis

Aim: The aim of the study was to compare serum ferritin and iron levels and periodontal status in pre- and post-menopausal female patients. Materials and Methods: A total of 108 systemically healthy patients were included in the study, 63 patients in the pre-menopause group and 45 patients in the post-menopause group. The periodontal diagnosis was made according to the new periodontal disease classification of the American Academy of Periodontology and the European Federation of Periodontology Serum Iron (mu g/dL) and Serum Ferritin (ng/mL) values were analysed in patients divided into groups according to menopausal status and periodontal status. Result: The mean ferritin in pre-menopausal women (34.96 +/- 27.87 ng/mL) was lower than the mean ferritin in post-menopausal women (64.24 +/- 36.05 ng/mL), and this difference was found to be statistically significant (P<0.001). There was no statistically significant difference between the averages of iron and ferritin according to periodontal diagnosis in pre-menopausal women (P = 0.200 and P = 0.858). A statistically significant difference was found between serum ferritin averages according to periodontal diagnosis in post-menopausal women (P < 0.001). Serum ferritin at % Interdental bone loss = 0 in Post-M was 33.93 +/- 8.65 ng/mL; 47.51 +/- 16.17 ng/mL in Stage 1 periodontitis; 72.66 +/- 18.12 ng/mL in Stage 2 periodontitis; It was found to be 87.4 +/- 47.1 ng/mL in Stage 3-4 periodontitis. Conclusion: Serum ferritin values might vary depending on the presence or severity of periodontitis in post-menopausal women.