The risk of fragment penetrating injury to the heart

被引:1
作者
Tsukada, Hirotaka [1 ]
Nguyen, Thuy-Tien N. [1 ]
Breeze, John [1 ,2 ]
Masouros, Spyros D. [1 ]
机构
[1] Imperial Coll London, Dept Bioengn, White City Campus, London SW7 2AZ, England
[2] Queen Elizabeth Hosp Birmingham, Royal Ctr Def Med, Birmingham, England
关键词
Secondary blast injury; Penetrating injury; Depth of penetration; Survival analysis; Injury-risk curve; Lamb heart; BLAST INJURIES; BIOMECHANICAL PROPERTIES; TERRORIST BOMBINGS; PORCINE ORGANS; MICROSTRUCTURE;
D O I
10.1016/j.jmbbm.2023.105776
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Injury due to the penetration of fragments into parts of the body has been the major cause of morbidity and mortality after an explosion. Penetrating injuries into the heart present very high mortality, yet the risk associated with such injuries has not been quantified. Quantifying this risk is key in the design of personal protection and the design of infrastructure.This study is the first quantitative assessment of cardiac penetrating injuries from energised fragments. Typical fragments (5-mm sphere, 0.78-g right-circular cylinder and 1.1-g chisel-nosed cylinder) were accelerated to a range of target striking velocities using a bespoke gas-gun system and impacted ventricular and atrial walls of lamb hearts. The severity of injury was shown to not depend on location (ventricular or atrial wall). The striking velocity with 50% probability of critical injury (Abbreviated Injury Scale (AIS) 5 score) ranged between 31 and 36 m/s across all 3 fragments used. These findings can help directly in reducing morbidity and mortality from explosive events as they can be implemented readily into models that aim to predict casualties in an explosive event, inform protocols for first responders, and improve design of infrastructure and personal protective equipment.
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页数:6
相关论文
共 33 条
  • [1] Wall stress determines systolic and diastolic function- Characteristics of heart failure
    Alter, Peter
    Koczulla, A. Rembert
    Nell, Christoph
    Figiel, Jens H.
    Vogelmeier, Claus F.
    Rominger, Marga B.
    [J]. INTERNATIONAL JOURNAL OF CARDIOLOGY, 2016, 202 : 685 - 693
  • [2] Bellamy RF, 1995, TXB MILITARY MED ANE, P1
  • [3] Bowen T.E., 1988, EMERGENCY WAR SURG, DOI [10.1001/archotol.1959.00730030805023, DOI 10.1001/ARCHOTOL.1959.00730030805023]
  • [4] Refrigeration and freezing of porcine tissue does not affect the retardation of fragment simulating projectiles
    Breeze, J.
    Carr, D. J.
    Mabbott, A.
    Beckett, S.
    Clasper, J. C.
    [J]. JOURNAL OF FORENSIC AND LEGAL MEDICINE, 2015, 32 : 77 - 83
  • [5] Breeze J., 2013, BRIT J ORAL MAX SURG, V51, P263
  • [6] Perforation of fragment simulating projectiles into goat skin and muscle
    Breeze, Johno
    James, G. R.
    Hepper, A. E.
    [J]. JOURNAL OF THE ROYAL ARMY MEDICAL CORPS, 2013, 159 (02) : 84 - 89
  • [7] Campbell NC, 1997, BRIT J SURG, V84, P1737, DOI 10.1046/j.1365-2168.1997.02819.x
  • [8] Duong M.T., 2015, International Biomechanics, V2, P79, DOI DOI 10.1080/23335432.2015.1049295
  • [9] 40 years of terrorist bombings - A meta-analysis of the casualty and injury profile
    Edwards, D. S.
    McMenemya, L.
    Stapley, S. A.
    Patel, H. D. L.
    Clasper, J. C.
    [J]. INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 2016, 47 (03): : 646 - 652
  • [10] Foale R., 1987, BRIT HEART J, V57, P396