Leishmaniasis: Recent epidemiological studies in the Middle East

被引:52
作者
Knight, Chinyere A. [1 ]
Harris, David R. [1 ]
Alshammari, Shifaa O. [2 ]
Gugssa, Ayele [3 ]
Young, Todd [3 ]
Lee, Clarence M. [3 ]
机构
[1] Tuskegee Univ, Dept Biol, Tuskegee, AL 36088 USA
[2] Univ Hafr Al Batin, Dept Biol, Hafar al Batin, Saudi Arabia
[3] Howard Univ, Dept Biol, Washington, DC 20059 USA
关键词
leishmaniasis; cutaneous; visceral; vector; Middle East; treatment; PHLEBOTOMINE SAND FLIES; AL-MUNAWARAH PROVINCE; CUTANEOUS LEISHMANIASIS; SAUDI-ARABIA; DIPTERA PSYCHODIDAE; NATURAL-PRODUCTS; DRUG; VACCINES; DISEASES; MADINAH;
D O I
10.3389/fmicb.2022.1052478
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Leishmaniasis, one of the most neglected tropical diseases (NTDs), is the third most important vector-borne disease worldwide. This disease has a global impact and severity of the infection and is greatest in the Middle East. The agent of infection is a protozoan parasite of the genus, Leishmania, and is generally transmitted by blood-sucking female sandflies. In humans, there are three clinical forms of infection: (1) cutaneous (CL), (2) mucocutaneous (ML), and (3) visceral leishmaniasis (VL). This review aims to discuss the current epidemiological status of leishmaniasis in Saudi Arabia, Iraq, Syria, and Yemen with a consideration of treatment options. The elevated risk of leishmaniasis is influenced by the transmission of the disease across endemic countries into neighboring non-infected regions.
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