Multifunctional wearable humidity and pressure sensors based on biocompatible graphene/bacterial cellulose bioaerogel for wireless monitoring and early warning of sleep apnea syndrome

被引:99
作者
Sun, Jingyao [1 ,2 ]
Xiu, Kunhao [1 ,2 ]
Wang, Ziying [1 ,2 ]
Hu, Ning [1 ,2 ]
Zhao, Libin [1 ,2 ]
Zhu, Hao [3 ]
Kong, Fanzhong [4 ]
Xiao, Jianliang [5 ]
Cheng, Lijin [1 ,2 ]
Bi, Xiaoyang [1 ,2 ]
机构
[1] Hebei Univ Technol, State Key Lab Reliabil & Intelligence Elect Equipm, Tianjin 300130, Peoples R China
[2] Hebei Univ Technol, Natl Engn Res Ctr Technol Innovat Method & Tool, Key Lab Hebei Prov Scale span Intelligent Equipmen, Sch Mech Engn,Key Lab Adv Intelligent Protect Equi, Tianjin 300401, Peoples R China
[3] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Orthoped Surg, Wuhan 430030, Hubei, Peoples R China
[4] Xinxing Cathay Int Intelligent Equipment & Technol, Beijing 100020, Peoples R China
[5] Univ Colorado Boulder, Dept Mech Engn, 427 UCB, Boulder, CO 80309 USA
关键词
Biocompatibility; Flexible pressure and humidity sensor; Physiological signal monitoring; Wireless respiration monitoring and decoding; Sleeping quality monitoring; REDUCED GRAPHENE OXIDE;
D O I
10.1016/j.nanoen.2023.108215
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Real time monitoring of respiratory status during sleep is essential to provide immediate feedback for people with sleep apnea syndrome (SAS). Conventional strategies to monitor sleeping status rely on polysomnography or inflexible chip sensors. However, the devices used in these methods have poor wearability and comfort and are inconvenient to operate. Here, we report a multifunctional, integrated and low-power wireless flexible sensing platform based on biocompatible bacterial cellulose (BC) and graphene hybrids, which can be used not only for monitoring physiological signals and respiration, but also for Morse-code-based wireless communication. Combining the excellent conductivity of graphene and the high mechanical properties of BC, 3D porous Gra-phene/BC bioaerogel exhibits outstanding pressure sensing properties with a wide operating range (20 pa to 30 kPa), high sensitivity and cycling stability. Moreover, graphene oxide (GO)/BC exhibits excellent humidity sensing performance and realizes real-time monitoring of respiratory waveform and frequency. Finally, wear wireless flexible pressure and humidity sensors for extended periods of time during sleep can provide simulta-neously diagnostic data for SAS. This original work shows that the wireless sensor system reported here has potential applicability in the field of medical science and military applications.
引用
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页数:13
相关论文
共 33 条
[1]   Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis [J].
Benjafield, Adam V. ;
Ayas, Najib T. ;
Eastwood, Peter R. ;
Heinzer, Raphael ;
Ip, Mary S. M. ;
Morrell, Mary J. ;
Nunez, Carlos M. ;
Patel, Sanjay R. ;
Penzel, Thomas ;
Pepin, Jean-Louis D. ;
Peppard, Paul E. ;
Sinha, Sanjeev ;
Tufik, Sergio ;
Valentine, Kate ;
Malhotra, Atul .
LANCET RESPIRATORY MEDICINE, 2019, 7 (08) :687-698
[2]   Global maternal health and newborn health: Looking backwards to learn from history [J].
Bergstrom, Staffan .
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY, 2016, 36 :3-13
[3]   Development of a flexible and highly sensitive pressure sensor based on an aramid nanofiber-reinforced bacterial cellulose nanocomposite membrane [J].
Chen, Shiqiang ;
Wang, Yidi ;
Fei, Bin ;
Long, Haofan ;
Wang, Tao ;
Zhang, Tonghua ;
Chen, Lei .
CHEMICAL ENGINEERING JOURNAL, 2022, 430
[4]   Smart facemask for wireless CO2 monitoring [J].
Escobedo, P. ;
Fernandez-Ramos, M. D. ;
Lopez-Ruiz, N. ;
Moyano-Rodriguez, O. ;
Martinez-Olmos, A. ;
de Vargas-Sansalvador, I. M. Perez ;
Carvajal, M. A. ;
Capitan-Vallvey, L. F. ;
Palma, A. J. .
NATURE COMMUNICATIONS, 2022, 13 (01)
[5]   Ultra-Robust and Extensible Fibrous Mechanical Sensors for Wearable Smart Healthcare [J].
Gao, Jiuwei ;
Fan, Yubo ;
Zhang, Qingtian ;
Luo, Lei ;
Hu, Xiaoqi ;
Li, Yue ;
Song, Juncai ;
Jiang, Hanjun ;
Gao, Xiaoyu ;
Zheng, Lu ;
Zhao, Wu ;
Wang, Zhenhua ;
Ai, Wei ;
Wei, Yuan ;
Lu, Qianbo ;
Xu, Manzhang ;
Wang, Yongtian ;
Song, Weitao ;
Wang, Xuewen ;
Huang, Wei .
ADVANCED MATERIALS, 2022, 34 (20)
[6]   Mechanically robust reduced graphene oxide/bacterial cellulose film obtained via biosynthesis for flexible supercapacitor [J].
Guan, Fangyi ;
Chen, Shiyan ;
Sheng, Nan ;
Chen, Ye ;
Yao, Jingjing ;
Pei, Qibing ;
Wang, Huaping .
CHEMICAL ENGINEERING JOURNAL, 2019, 360 :829-837
[7]   Respiratory rate variability in sleeping adults without obstructive sleep apnea [J].
Gutierrez, Guillermo ;
Williams, Jeffrey ;
Alrehaili, Ghadah A. ;
McLean, Anna ;
Pirouz, Ramin ;
Amdur, Richard ;
Jain, Vivek ;
Ahari, Jalil ;
Bawa, Amandeep ;
Kimbro, Shawn .
PHYSIOLOGICAL REPORTS, 2016, 4 (17)
[8]   Flexible, non-contact and multifunctional humidity sensors based on two-dimensional phytic acid doped co-metal organic frameworks nanosheets [J].
Huo, Yanming ;
Bu, Miaomiao ;
Ma, Zongtao ;
Sun, Jingyao ;
Yan, Yuhua ;
Xiu, Kunhao ;
Wang, Ziying ;
Hu, Ning ;
Li, Yun-Fei .
JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2022, 607 :2010-2018
[9]   A Systematic Review of Sensing Technologies for Wearable Sleep Staging [J].
Imtiaz, Syed Anas .
SENSORS, 2021, 21 (05) :1-21
[10]   Assessment of Occlusal Force and Local Gas Release Using Degradable Bacterial Cellulose/Ti3C2Tx MXene Bioaerogel for Oral Healthcare [J].
Jin, Xiujuan ;
Li, Linlin ;
Zhao, Shufang ;
Li, Xiaohong ;
Jiang, Kai ;
Wang, Lili ;
Shen, Guozhen .
ACS NANO, 2021, 15 (11) :18385-18393