Isoamyl (E)-3-(3,4-Dimethoxyphenyl)acrylate

被引：0
作者：
Pamela, Egar [1 ]
Atmaja, Lukman [1 ]
Santoso, Mardi [1 ]
机构：
[1] Inst Teknol Sepuluh Nopember, Fac Sci & Analyt Data, Dept Chem, Kampus ITS Sukolilo, Surabaya 60111, Indonesia
来源：
MOLBANK | 2023年 / 2023卷 / 03期
关键词：
synthesis; isoamyl (E)-3-(3,4-dimethoxyphenyl)acrylate; sun protection factor; ESTERIFICATION;
D O I：
10.3390/M1708
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Isoamyl (E)-3-(3,4-dimethoxyphenyl)acrylate (1) was obtained from the 2-methyl-6-nitrobenzoic anhydride (MNBA)/4-dimethylaminopyridine (DMAP)-catalyzed reaction at room temperature for 190 min in dichloromethane with a yield of 95%. The structure of isoamyl (E)-3-(3,4-dimethoxyphenyl)acrylate (1) was elucidated using NMR, FTIR, and high-resolution mass spectrometry. In vitro sun protection factor evaluation exhibited a value of 37.10 +/- 0.03 which indicates that isoamyl (E)-3-(3,4-dimethoxyphenyl)acrylate (1) is a sunscreen agent with high protection.
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页数：5
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