Effect of tumor microenvironment on ferroptosis: inhibition or promotion

被引：6
作者：
Xia, Zhengzhen [1 ]
Quan, Yi [1 ,2 ]
机构：
[1] Guangdong Med Univ, Clin Med Sch 1, Zhanjiang, Guangdong, Peoples R China
[2] First Peoples Hosp Zhaoqing, Dept Oncol Med Ctr, Zhaoqing, Guangdong, Peoples R China
来源：
FRONTIERS IN ONCOLOGY | 2023年 / 13卷
关键词：
ferroptosis; tumor microenvironment; tumor immunotherapy; lipid peroxidation; micro RNA; MESENCHYMAL TRANSITION; SUPPRESSOR-CELLS; LACTIC-ACID; CANCER; INFLAMMATION; MACROPHAGES; DYSFUNCTION; PROGRESSION; RESISTANCE; APOPTOSIS;
D O I：
10.3389/fonc.2023.1155511
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Ferroptosis is a type of lipid peroxidation-induced, iron-dependent programmed cell death. Emerging evidence suggests that ferroptosis is intimately connected to tumorigenesis, development, treatment and plays a major role in tumor immune regulation. This study focused on the connection between ferroptosis and immune regulation, which may offer a theoretical basis for targeting ferroptosis and tumor immunotherapy.
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页数：8
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