Advances in the Treatment of Pediatric Brain Tumors

被引：11
|
作者：
Kulubya, Edwin S. [1 ]
Kercher, Matthew J. [1 ]
Phillips, H. Westley [2 ]
Antony, Reuben [3 ]
Edwards, Michael S. B. [1 ]
机构：
[1] Univ Calif Davis, Dept Neurosurg, Sacramento, CA 95817 USA
[2] Univ Pittsburgh, Childrens Hosp Pittsburgh, Dept Neurosurg, Med Ctr, Pittsburgh, PA 15224 USA
[3] Univ Calif Davis, Dept Pediat, Sacramento, CA 95817 USA
来源：
CHILDREN-BASEL | 2023年 / 10卷 / 01期
关键词：
pediatrics; brain tumors; glioma; medulloblastoma; ependymoma; immunotherapy; targeted therapy; laser interstitial therapy; LOW-GRADE GLIOMAS; ATYPICAL TERATOID/RHABDOID TUMORS; CENTRAL-NERVOUS-SYSTEM; CONVECTION-ENHANCED DELIVERY; INDUCED THERMAL THERAPY; MOLECULAR SUBGROUPS; CHILDHOOD MEDULLOBLASTOMA; RESPONSE ASSESSMENT; CHILDREN; CLASSIFICATION;
D O I：
10.3390/children10010062
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Pediatric brain tumors are the most common solid malignancies in children. Advances in the treatment of pediatric brain tumors have come in the form of imaging, biopsy, surgical techniques, and molecular profiling. This has led the way for targeted therapies and immunotherapy to be assessed in clinical trials for the most common types of pediatric brain tumors. Here we review the latest efforts and challenges in targeted molecular therapy, immunotherapy, and newer modalities such as laser interstitial thermal therapy.
引用
收藏
页数：15
相关论文
共 50 条
  • [31] Advances in Focused Ultrasound for the Treatment of Brain Tumors
    Rao, Rohan
    Patel, Anjali
    Hanchate, Kunal
    Robinson, Eric
    Edwards, Aniela
    Shah, Sanjit
    Higgins, Dominique
    Haworth, Kevin J.
    Lucke-Wold, Brandon
    Krummel, Daniel Pomeranz
    Sengupta, Soma
    TOMOGRAPHY, 2023, 9 (03) : 1094 - 1109
  • [32] Current concepts in radiologic assessment of pediatric brain tumors during treatment, part 1
    D'Arco, Felice
    Culleton, Sinead
    De Cocker, Laurens J. L.
    Mankad, Kshitij
    Davila, Jorge
    Tamrazi, Benita
    PEDIATRIC RADIOLOGY, 2018, 48 (13) : 1833 - 1843
  • [33] CAR T Cell Therapy's Potential for Pediatric Brain Tumors
    Thomas, Pauline
    Galopin, Natacha
    Bonerandi, Emma
    Clemenceau, Beatrice
    Fougeray, Sophie
    Birkle, Stephane
    CANCERS, 2021, 13 (21)
  • [34] Transcriptomic observations of intra and extracellular immunotherapy targets for pediatric brain tumors
    Frederico, Stephen C.
    Raphael, Itay
    Nisnboym, Michal
    Huq, Sakibul
    Schlegel, Brent T.
    Sneiderman, Chaim T.
    Jackson, Sydney A.
    Jain, Anya
    Olin, Michael R.
    Rood, Brian R.
    Pollack, Ian F.
    Hwang, Eugene I.
    Rajasundaram, Dhivyaa
    Kohanbash, Gary
    EXPERT REVIEW OF CLINICAL IMMUNOLOGY, 2024, 20 (11) : 1411 - 1420
  • [35] Pediatric brain tumors: a histologic and genetic update on commonly encountered entities
    Dunham, Christopher
    SEMINARS IN DIAGNOSTIC PATHOLOGY, 2010, 27 (03) : 147 - 159
  • [36] Pediatric embryonal brain tumors in the molecular era
    Li, Bryan K.
    Al-Karmi, Salma
    Huang, Annie
    Bouffet, Eric
    EXPERT REVIEW OF MOLECULAR DIAGNOSTICS, 2020, 20 (03) : 293 - 303
  • [37] Neuropathology of Pediatric Brain Tumors: A Concise Review
    Cole, Bonnie L.
    NEUROSURGERY, 2022, 90 (01) : 7 - 15
  • [38] Different Treatment Strategies for Pediatric Brain Tumors
    Fiorillo, Amedeo
    CURRENT PEDIATRIC REVIEWS, 2008, 4 (03) : 178 - 186
  • [39] Chemoradiotherapy for pediatric brain tumors
    Kubo, O
    Takakura, K
    CRITICAL REVIEWS IN NEUROSURGERY, 1998, 8 (06) : 357 - 363
  • [40] Pediatric Brain Tumors: An Update
    Segal, Devorah
    Karajannis, Matthias A.
    CURRENT PROBLEMS IN PEDIATRIC AND ADOLESCENT HEALTH CARE, 2016, 46 (07) : 242 - 250
12345