Advances in the Treatment of Pediatric Brain Tumors

被引：11
|
作者：
Kulubya, Edwin S. [1 ]
Kercher, Matthew J. [1 ]
Phillips, H. Westley [2 ]
Antony, Reuben [3 ]
Edwards, Michael S. B. [1 ]
机构：
[1] Univ Calif Davis, Dept Neurosurg, Sacramento, CA 95817 USA
[2] Univ Pittsburgh, Childrens Hosp Pittsburgh, Dept Neurosurg, Med Ctr, Pittsburgh, PA 15224 USA
[3] Univ Calif Davis, Dept Pediat, Sacramento, CA 95817 USA
来源：
CHILDREN-BASEL | 2023年 / 10卷 / 01期
关键词：
pediatrics; brain tumors; glioma; medulloblastoma; ependymoma; immunotherapy; targeted therapy; laser interstitial therapy; LOW-GRADE GLIOMAS; ATYPICAL TERATOID/RHABDOID TUMORS; CENTRAL-NERVOUS-SYSTEM; CONVECTION-ENHANCED DELIVERY; INDUCED THERMAL THERAPY; MOLECULAR SUBGROUPS; CHILDHOOD MEDULLOBLASTOMA; RESPONSE ASSESSMENT; CHILDREN; CLASSIFICATION;
D O I：
10.3390/children10010062
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Pediatric brain tumors are the most common solid malignancies in children. Advances in the treatment of pediatric brain tumors have come in the form of imaging, biopsy, surgical techniques, and molecular profiling. This has led the way for targeted therapies and immunotherapy to be assessed in clinical trials for the most common types of pediatric brain tumors. Here we review the latest efforts and challenges in targeted molecular therapy, immunotherapy, and newer modalities such as laser interstitial thermal therapy.
引用
收藏
页数：15
相关论文
共 50 条
  • [1] Essential Management of Pediatric Brain Tumors
    Lutz, Katharina
    Juenger, Stephanie T.
    Messing-Juenger, Martina
    CHILDREN-BASEL, 2022, 9 (04):
  • [2] Advances in the molecular classification of pediatric brain tumors: a guide to the galaxy
    Cacciotti, Chantel
    Fleming, Adam
    Ramaswamy, Vijay
    JOURNAL OF PATHOLOGY, 2020, 251 (03): : 249 - 261
  • [3] Advances on Epigenetic Drugs for Pediatric Brain Tumors
    Skouras, Panagiotis
    Markouli, Mariam
    Strepkos, Dimitrios
    Piperi, Christina
    CURRENT NEUROPHARMACOLOGY, 2023, 21 (07) : 1519 - 1535
  • [4] Advances in Treatment of Pediatric Brain Tumors
    Robertson P.L.
    NeuroRX, 2006, 3 (2): : 276 - 291
  • [5] Leptomeningeal dissemination in pediatric brain tumors
    Cocito, Carolina
    Martin, Brice
    Giantini-Larsen, Alexandra M.
    Valcarce-Aspegren, Marcus
    Souweidane, Mark M.
    Szalontay, Luca
    Dahmane, Nadia
    Greenfield, Jeffrey P.
    NEOPLASIA, 2023, 39
  • [6] Review of molecular classification and treatment implications of pediatric brain tumors
    Stucklin, Ana S. Guerreiro
    Ramaswamy, Vijay
    Daniels, Craig
    Taylor, Michael D.
    CURRENT OPINION IN PEDIATRICS, 2018, 30 (01) : 3 - 9
  • [7] Advances in Targeted Therapies for Pediatric Brain Tumors
    Mueller, Timothy
    Stucklin, Ana Sofia Guerreiro
    Postlmayr, Andreas
    Metzger, Sarah
    Gerber, Nicolas
    Kline, Cassie
    Grotzer, Michael
    Nazarian, Javad
    Mueller, Sabine
    CURRENT TREATMENT OPTIONS IN NEUROLOGY, 2020, 22 (12)
  • [8] Advances in Targeted Therapies for Pediatric Brain Tumors
    Timothy Mueller
    Ana Sofia Guerreiro Stucklin
    Andreas Postlmayr
    Sarah Metzger
    Nicolas Gerber
    Cassie Kline
    Michael Grotzer
    Javad Nazarian
    Sabine Mueller
    Current Treatment Options in Neurology, 2020, 22
  • [9] Update on Pediatric Brain Tumors: the Molecular Era and Neuro-immunologic Beginnings
    Duke, Elizabeth S.
    Packer, Roger J.
    CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS, 2020, 20 (08)
  • [10] Advances in the classification and treatment of pediatric brain tumors
    Fangusaro, Jason
    Bandopadhayay, Pratiti
    CURRENT OPINION IN PEDIATRICS, 2021, 33 (01) : 26 - 32
12345