Advances in the Treatment of Pediatric Brain Tumors

被引：14

作者：

Kulubya, Edwin S. ^{[1
]}

Kercher, Matthew J. ^{[1
]}

Phillips, H. Westley ^{[2
]}

Antony, Reuben ^{[3
]}

Edwards, Michael S. B. ^{[1
]}

机构：

[1] Univ Calif Davis, Dept Neurosurg, Sacramento, CA 95817 USA

[2] Univ Pittsburgh, Childrens Hosp Pittsburgh, Dept Neurosurg, Med Ctr, Pittsburgh, PA 15224 USA

[3] Univ Calif Davis, Dept Pediat, Sacramento, CA 95817 USA

来源：

CHILDREN-BASEL | 2023年 / 10卷 / 01期

关键词：

pediatrics; brain tumors; glioma; medulloblastoma; ependymoma; immunotherapy; targeted therapy; laser interstitial therapy; LOW-GRADE GLIOMAS; ATYPICAL TERATOID/RHABDOID TUMORS; CENTRAL-NERVOUS-SYSTEM; CONVECTION-ENHANCED DELIVERY; INDUCED THERMAL THERAPY; MOLECULAR SUBGROUPS; CHILDHOOD MEDULLOBLASTOMA; RESPONSE ASSESSMENT; CHILDREN; CLASSIFICATION;

D O I：

10.3390/children10010062

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Pediatric brain tumors are the most common solid malignancies in children. Advances in the treatment of pediatric brain tumors have come in the form of imaging, biopsy, surgical techniques, and molecular profiling. This has led the way for targeted therapies and immunotherapy to be assessed in clinical trials for the most common types of pediatric brain tumors. Here we review the latest efforts and challenges in targeted molecular therapy, immunotherapy, and newer modalities such as laser interstitial thermal therapy.

引用

页数：15

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