Targeting SHP2 Signaling in Lung Cancer

被引:6
作者
Imbody, Denis [1 ]
Arce, Keishla [2 ]
Solank, Hitendra S. [1 ]
Haura, Eric B. [1 ,3 ]
Pellini, Bruna [1 ,3 ]
机构
[1] H Lee Moffitt Canc Ctr & Res Inst, Dept Thorac Oncol, 2902 Magnolia Dr, Tampa, FL 33612 USA
[2] Ponce Hlth Sci Univ, Sch Med, Ponce, PR USA
[3] Univ S Florida, Morsani Coll Med, Dept Oncol Sci, Tampa, FL USA
关键词
SHP2; inhibitors; RAS pathway; signaling; RTKs; PD-1; pathway; TYROSINE-PHOSPHATASE; ANTITUMOR IMMUNITY; INHIBITION; RMC-4630; PHOSPHORYLATION; ACTIVATION; RESISTANCE;
D O I
10.1016/j.jtho.2023.08.009
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
[No abstract available]
引用
收藏
页码:18 / 24
页数:7
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