Validation of the German Registry for Acute Aortic Dissection Type A Score in predicting 30-day mortality after type A aortic dissection surgery

被引:11
|
作者
Gemelli, Marco [1 ,2 ]
Di Tommaso, Ettorino [1 ]
Natali, Roberto [1 ]
Dixon, Lauren Kari [1 ]
Ahmed, Eltayeb Mohamed [1 ]
Rajakaruna, Cha [1 ]
Bruno, Vito D. [1 ,3 ,4 ]
机构
[1] Univ Hosp Bristol & Weston NHS Fdn Trust, Bristol Heart Inst, Cardiothorac Surg, Bristol, England
[2] Univ Padua, Dept Cardiac Thorac Vasc & Publ Hlth Sci, Padua, Italy
[3] Univ Bristol, Cardiovasc Translat Hlth Sci, Bristol, England
[4] Univ Bristol, Bristol Royal Infirm, Cardiovasc Translat Hlth Sci, Res Floor Level 7,Queens Bldg,Upper Maudlin St, Bristol BS2, England
关键词
Aortic dissection; German Registry of Acute Type A Dissection; European System for Cardiac Operative Risk Evaluation; Risk prediction; Malperfusion; GERAADA SCORE; EUROSCORE II; OUTCOMES;
D O I
10.1093/ejcts/ezad141
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVESNo reliable scores are available to predict mortality following surgery for type A acute aortic dissection (TAAAD). Recently, the German Registry of Acute Aortic Dissection Type A (GERAADA) score has been developed. We aim to compare how the GERAADA score performs in predicting operative mortality for TAAAD to the European System for Cardiac Operative Risk Evaluation (EuroSCORE) II.METHODSWe calculated the GERAADA score and EuroSCORE II in patients who underwent TAAAD repair at the Bristol Heart Institute. As there are no precise criteria to calculate the GERAADA score, we used 2 methods: a Clinical-GERAADA score, which evaluated malperfusion with clinical and radiological evidence, and a Radiological-GERAADA score, where malperfusion was assessed by computed tomography scan alone.RESULTS207 consecutive patients had surgery for TAAAD, and the observed 30-day mortality was 15%. The Clinical-GERAADA score showed the strongest discriminative power with an area under the curve (AUC) of 0.80 [95% confidence interval (CI) 0.71-0.89], while the Radiological-GERAADA score had an AUC of 0.77 (95% CI 0.67-0.87). EuroSCORE II showed acceptable discriminative power with an AUC of 0.77 (95% CI 0.67-0.87).CONCLUSIONSClinical GERAADA score performed better than the other scores and it is specific and easy to use in the context of a TAAAD. Further validation of the new criteria for malperfusion is needed.
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页数:8
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