Neuroscience of reward: Paradoxical roles for corticotrophin-releasing factor

被引：0
作者：
Rossi, Mark A. [1 ]
机构：
[1] Rutgers State Univ, Child Hlth Inst New Jersey, Robert Wood Johnson Med Sch, Dept Pediat,Brain Hlth Inst, New Brunswick, NJ 08901 USA
来源：
CURRENT BIOLOGY | 2024年 / 34卷 / 02期
关键词：
DOPAMINERGIC-NEURONS; NUCLEUS-ACCUMBENS; TERMINALS; RECEPTOR;
D O I：
10.1016/j.cub.2023.12.022
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The brain has long been known to control stress and reward through complex and interconnected circuitry. A new study now reveals a group of hypothalamic neurons that paradoxically mediate both reward and aversion.
引用
收藏
页数：4
相关论文
共 18 条
  • [1] Corticotropin releasing hormone, receptor regulation and the stress response
    Aguilera, G
    [J]. TRENDS IN ENDOCRINOLOGY AND METABOLISM, 1998, 9 (08) : 329 - 336
  • [2] Conrad CD, 2008, REV NEUROSCIENCE, V19, P395
  • [3] Hypothalamic CRH neurons orchestrate complex behaviours after stress
    Fuzesi, Tamas
    Daviu, Nuria
    Cusulin, Jaclyn I. Wamsteeker
    Bonin, Robert P.
    Bains, Jaideep S.
    [J]. NATURE COMMUNICATIONS, 2016, 7
  • [4] Illuminating subcortical GABAergic and glutamatergic circuits for reward and aversion
    Gordon-Fennell, Adam
    Stuber, Garret D.
    [J]. NEUROPHARMACOLOGY, 2021, 198
  • [5] The Yin and Yang of dopamine release: a new perspective
    Goto, Yukiori
    Otani, Satoru
    Grace, Anthony A.
    [J]. NEUROPHARMACOLOGY, 2007, 53 (05) : 583 - 587
  • [6] Dopamine reward circuitry: Two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex
    Ikemoto, Satoshi
    [J]. BRAIN RESEARCH REVIEWS, 2007, 56 (01) : 27 - 78
  • [7] Rapid, biphasic CRF neuronal responses encode positive and negative valence
    Kim, Jineun
    Lee, Seongju
    Fang, Yi-Ya
    Shin, Anna
    Park, Seahyung
    Hashikawa, Koichi
    Bhat, Shreelatha
    Kim, Daesoo
    Sohn, Jong-Woo
    Li, Dayu
    Suh, Greg S. B.
    [J]. NATURE NEUROSCIENCE, 2019, 22 (04) : 576 - +
  • [8] Rajamanickam S., 2022, CURR OPIN ENDOCR MET, V26, DOI [10.1016/j.coemr.2022.100400, DOI 10.1016/J.COEMR.2022.100400]
  • [9] Glutamatergic and Dopaminergic Neurons Mediate Anxiogenic and Anxiolytic Effects of CRHR1
    Refojo, Damian
    Schweizer, Martin
    Kuehne, Claudia
    Ehrenberg, Stefanie
    Thoeringer, Christoph
    Vogl, Annette M.
    Dedic, Nina
    Schumacher, Marion
    von Wolff, Gregor
    Avrabos, Charilaos
    Touma, Chadi
    Engblom, David
    Schuetz, Guenther
    Nave, Klaus-Armin
    Eder, Matthias
    Wotjak, Carsten T.
    Sillaber, Inge
    Holsboer, Florian
    Wurst, Wolfgang
    Deussing, Jan M.
    [J]. SCIENCE, 2011, 333 (6051) : 1903 - 1907
  • [10] NEUROENDOCRINE CRF MOTONEURONS - INTRAHYPOTHALAMIC AXON TERMINALS SHOWN WITH A NEW RETROGRADE-LUCIFER-IMMUNO METHOD
    RHO, JH
    SWANSON, LW
    [J]. BRAIN RESEARCH, 1987, 436 (01) : 143 - 147
12