Essential oil and its nanoemulsion of Eucalyptus cladocalyx: chemical characterization, antioxidant, anti-inflammatory and anticancer activities

被引：2
|
作者：
Dakhlaoui, Sarra [1 ,2 ]
Bourgou, Soumaya [2 ]
Kalai, Feten Zar [2 ,3 ]
Hammami, Majdi [2 ]
Essafi, Makram [4 ]
Jallouli, Slim [5 ]
Msaada, Kamel [2 ]
机构：
[1] Tunis El Manar Univ, Coll Sci Tunis, Tunis, Tunisia
[2] Biotechnol Ctr Borj Cedria Technopole, Lab Aromat & Med Plants LAMP, Hammam Lif, Tunisia
[3] Univ Tsukuba, Grad Sch Life & Environm Sci, Tsukuba, Japan
[4] Pasteur Inst Tunis, Lab Transmiss Control & Immunobiol Infect LTCII, LR11 IPT02, Tunis, Tunisia
[5] Biotechnol Ctr Borj Cedria, Lab Bioact Subst LSBA, Hammam Lif, Tunisia
来源：
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH | 2024年 / 34卷 / 08期
关键词：
Eucalyptus cladocalyx; essential oil; nanoemulsion; stability; biological activities; SPONTANEOUS EMULSIFICATION; BIOLOGICAL-ACTIVITIES; STABILITY; ANTIBACTERIAL;
D O I：
10.1080/09603123.2023.2280119
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Formulating a nanoemulsion (NE) of essential oil (EO) could enhance its efficiency while requiring lower concentrations. Eucalyptus cladocalyx F. Muell EO was rich in monoterpenes hydrocarbons. NE was prepared and the effect of surfactant (Tween 20, 40 and 80) and shearing time were investigated. The results showed that the best NE was formed using Tween 80 after 25 min of emulsification. Small droplet size (40 nm), low polydispersity index PDI (0.49), and stable zeta potential highlighted the excellent NE stability which was tested under storage conditions for 4 months. The results showed that the antioxidant and anticancer activities of NE were enhanced compared to free EO. Furthermore, NE and EO exhibited high anti-inflammatory effects by inhibiting nitric oxide (NO), Interleukin 6 (IL-6), and tumor necrosis factors alpha (TNF-alpha) production in liposaccharides (LPS)-induced RAW264.7 cells. In conclusion, a stable Eucalyptus cladocalyx-NE was produced, with improved biological activities.
引用
收藏
页码：2899 / 2912
页数：14
相关论文
共 50 条
  • [41] Antioxidant, analgesic and anti-inflammatory effects of lavender essential oil
    Da Silva, Gabriela L.
    Luft, Carolina
    Lunardelli, Adroaldo
    Amaral, Robson H.
    Da Silva Melo, Denizar A.
    Donadio, Marcio V. F.
    Nunes, Fernanda B.
    De Azambuja, Marcos S.
    Santana, Joao C.
    Moraes, Cristina M. B.
    Mello, Ricardo O.
    Cassel, Eduardo
    De Almeida Pereira, Marcos Aurelio
    De Oliveira, Jarbas R.
    ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS, 2015, 87 (02): : 1397 - 1408
  • [42] Antioxidant and anti-inflammatory activities of quercetin and its derivatives
    Lesjak, Marija
    Beara, Ivana
    Simin, Natasa
    Pintac, Diandra
    Majkic, Tatjana
    Bekvalac, Kristina
    Orcic, Dejan
    Mimica-Dukic, Neda
    JOURNAL OF FUNCTIONAL FOODS, 2018, 40 : 68 - 75
  • [43] A Review of Recent Curcumin Analogues and Their Antioxidant, Anti-Inflammatory, and Anticancer Activities
    Kaur, Kirandeep
    Al-Khazaleh, Ahmad K.
    Bhuyan, Deep Jyoti
    Li, Feng
    Li, Chun Guang
    ANTIOXIDANTS, 2024, 13 (09)
  • [44] ANTIOXIDANT, ANTI-INFLAMMATORY AND ANTICANCER ACTIVITIES OF THE MEDICINAL HALOPHYTE REAUMURIA VERMICULATA
    Karker, Manel
    Falleh, Hanen
    Msaada, Kamel
    Smaoui, Abderrazak
    Abdelly, Chedly
    Legault, Jean
    Ksouri, Riadh
    EXCLI JOURNAL, 2016, 15 : 297 - 307
  • [45] Antioxidant, Anti-Inflammatory, Antimicrobial, and Anticancer Activities of Pomegranate Juice Concentrate
    Habib, Hosam M.
    El-Gendi, Hamada
    El-Fakharany, Esmail M.
    El-Ziney, Mohamed G.
    El-Yazbi, Ahmed F.
    Al Meqbaali, Fatima T.
    Ibrahim, Wissam H.
    NUTRIENTS, 2023, 15 (12)
  • [46] Antioxidant, antimicrobial, anti-inflammatory and anticancer activities of Carthamus tinctorius flowers
    Bouraoui, N. K.
    Oueslati, S.
    Falleh, H.
    Harbaoui, F.
    Ksouri, R.
    Legault, J.
    Lachaal, M.
    PLANTA MEDICA, 2011, 77 (12) : 1433 - 1433
  • [47] Eucalyptus cinerea: Microscopic Profile, Chemical Composition of Essential Oil and its Antioxidant, Microbiological and Cytotoxic Activities
    Pauzer, Matheus Saukoski
    Borsato, Thais de Oliveira
    de Almeida, Valter Paes
    Raman, Vijayasankar
    Justus, Barbara
    Pereira, Camila Bugnotto
    Flores, Thiago Bevilacqua
    Noronha Sales Maia, Beatriz Helena Lameiro
    Meneghetti, Emanuelle Kretz
    Kanunfre, Carla Cristine
    Padilha de Paula, Josiane de Fatima
    Farago, Paulo Vitor
    Budel, Jane Manfron
    BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY, 2021, 64 : 1 - 19
  • [48] Chemical Composition and Potential of Eucalyptus camaldulensis Dehnh. Essential Oil and Its Major Components as Anti-inflammatory and Anti-leishmanial Agent
    Grewal, Kamaljit
    Joshi, Jyoti
    Rathee, Sonia
    Kaur, Sukhbir
    Singh, Harminder Pal
    Batish, Daizy R.
    JOURNAL OF ESSENTIAL OIL BEARING PLANTS, 2022, 25 (03) : 419 - 429
  • [49] Antioxidant, Anti-Inflammatory, and Anti-Bacterial Activities of Artemisia vulgaris L. Essential Oil in Vietnam
    Trinh, Pham Thi Nhat
    Tien, Le Xuan
    Danh, Tong Thanh
    Hang, Dang Thi Le
    Hoa, Nguyen Van
    Yen, To Thi Bao
    Dung, Le Tien
    NATURAL PRODUCT COMMUNICATIONS, 2024, 19 (08)
  • [50] Chemical Composition, Allelopathic, Antioxidant, and Anti-Inflammatory Activities of Sesquiterpenes Rich Essential Oil of Cleome amblyocarpa Barratte & Murb.
    Abd-ElGawad, Ahmed M.
    Elgamal, Abdelbaset M.
    EI-Amier, Yasser A.
    Mohamed, Tarik A.
    El Gendy, Abd El-Nasser G.
    I. Elshamy, Abdelsamed
    PLANTS-BASEL, 2021, 10 (07):
12345