Predictive Value of C-Reactive Protein to Albumin Ratio for Amputation Risk in Diabetic Foot Infection

被引:2
作者
Karaca, Banu [1 ]
Ormen, Bahar [1 ]
Kiris, Tuncay [2 ,3 ]
Sener, Alper [1 ]
机构
[1] Izmir Katip Celebi Univ, Ataturk Training & Res Hosp, Dept Infect Dis, Izmir, Turkiye
[2] Izmir Katip Celebi Univ, Ataturk Training & Res Hosp, Dept Cardiol, Izmir, Turkiye
[3] Izmir Katip Celebi Univ, Ataturk Training & Res Hosp, Dept Cardiol, TR-35360 Izmir, Turkiye
关键词
diabetic foot infection; c-reactive protein/albumin ratio; amputation; ULCERS; MANAGEMENT; DISEASE;
D O I
10.1177/00033197231218330
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Diabetic foot infections are one of the complications of diabetes mellitus resulting in extremity amputation and mortality. This study aimed to examine the predictive value of the C-reactive protein (CRP) to albumin ratio (CAR) for amputation risk in diabetic foot infection. Data from 178 patients were retrospectively examined. We found the cut point value of 15.45 according to the receiver operating characteristic (ROC) curve to show the predictive value of CAR for amputation risk in the overall population. We then divided the patients into two groups low (<15.45, n = 96) and high risk (>= 15.45, n = 82) according to their CAR value. Matching based on propensity scores produced 64 patients in each group and showed that the amputation rate was high in the high-risk groups (50 vs 25%, P = .003). In the multivariate analysis in the matching group, previous amputation, antibiotic therapy in the last 3 months, and CAR (Odds ratio [OR]: 1.30, 95%Confidence interval [CI]: 1.01-1.45, P < .001) were independent predictors of amputation. These parameters may be useful to predict amputation risk in these patient groups.
引用
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页数:7
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