Scedosporium infection disseminated "from toe to head" in allogeneic stem cell transplant recipient: a case report

被引:4
|
作者
Marinovic, Debra A. [1 ]
Bhaimia, Eric [1 ]
Forrest, Graeme N. [2 ]
LaRue, Rebecca [3 ]
Nathan, Sunita [1 ]
Ustun, Celalettin [1 ]
Ward, Anna [1 ]
机构
[1] Rush Univ, Dept Internal Med, Div Hematol Oncol & Cell Therapy, Med Ctr, 1725 W Harrison St Suite 809, Chicago, IL 60612 USA
[2] Rush Univ, Dept Internal Med, Div Infect Dis, Med Ctr, Chicago, IL USA
[3] Rush Univ, Dept Pharm, Med Ctr, Chicago, IL USA
关键词
Scedosporium; Allogeneic transplant; Invasive fungal disease; Case report; OSTEOMYELITIS; APIOSPERMUM; GUIDELINES; MANAGEMENT; DIAGNOSIS;
D O I
10.1186/s12879-023-08345-2
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
BackgroundScedosporium is a lesser-known non-Aspergillus genus of mold that can present in unsuspecting ways. If overlooked, it may disseminate and cause high mortality in high-risk allogeneic stem cell transplant recipients.Case presentationThis case report describes a 65-year-old patient with Acute Myeloid Leukemia who underwent an allogeneic hematopoietic stem cell transplant after a period of prolonged neutropenia with fluconazole prophylaxis. She suffered severe debility with altered mentation from a S. apiospermum infection which likely disseminated from a toe wound to the lung and central nervous system. She was successfully treated with liposomal amphotericin B and voriconazole, but faced a prolonged recovery from physical and neurologic sequela.ConclusionsThe case highlights the importance of adequate anti-mold prophylaxis in high-risk patients, and the value of a thorough physical examination in this patient population, with particular attention to skin and soft tissue findings.
引用
收藏
页数:5
相关论文
共 50 条
  • [21] Visceral disseminated varicella zoster virus infection following COVID-19 vaccination in an allogeneic stem cell transplant recipient
    Nishimoto, Mitsutaka
    Sogabe, Nobuhiro
    Hino, Masayuki
    TRANSPLANT INFECTIOUS DISEASE, 2022, 24 (02)
  • [22] Strongyloides stercoralis infection in allogeneic stem cell transplant: a case report and review of the literature
    Iori, A. P.
    Ferretti, A.
    Gentile, G.
    Gabrielli, S.
    Perrone, S.
    Barberi, W.
    Torelli, G. F.
    Natalino, F.
    Scalzulli, E.
    Totino, V.
    Foa, R.
    Cancrini, G.
    Girmenia, C.
    TRANSPLANT INFECTIOUS DISEASE, 2014, 16 (04) : 625 - 630
  • [23] Rhodococcus globerulus bacteremia in an allogeneic hematopoietic stem cell transplant recipient: report of the first transplant case and review of the literature
    Ramanan, P.
    Deziel, P. J.
    Razonable, R. R.
    TRANSPLANT INFECTIOUS DISEASE, 2014, 16 (03) : 484 - 489
  • [25] Response to Trimethoprim-Sulfamethoxazole in a Pediatric Hematopoietic Stem Cell Transplant Recipient With Disseminated Toxoplasmosis: A Case Report
    Khan, Aslam
    Schwenk, Hayden T.
    Kohlman, Krystal
    Bertaina, Alice
    Cho, Stephanie
    Montoya, Jose G.
    Contopoulos-Ioannidis, Despina
    JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY, 2021, 10 (06) : 745 - 748
  • [26] Disseminated Rhinocladiella mackenziei infection in a kidney transplant recipient: A case report and literature review
    Al Otaibi, Torki M.
    Gheith, Osama A.
    Alobaid, Khaled
    Nair, Prasad
    Eldein, Sohair M. Zein
    Mahmoud, Tarek S.
    Halim, Medhat A.
    Aboatya, Hasaneen H.
    Balaha, Mohamed A.
    Atea, Khalid A.
    Nagib, Ayman Maher
    Al-Hatmi, Abdullah M. S.
    Sadon, Amal
    Meis, Jacques F.
    Zahab, Mohamed
    JOURNAL DE MYCOLOGIE MEDICALE, 2021, 31 (04):
  • [27] Successful treatment of disseminated Verruconis gallopava infection in a heart transplant recipient: A case report
    Martin, Marlee
    Hobbs, Athena L., V
    Baird, Mallory
    AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY, 2022, 79 (13) : 1066 - 1069
  • [28] DISSEMINATED RHINOCLADIELLA MACKENZIEI INFECTION IN A KIDNEY TRANSPLANT RECIPIENT: CASE REPORT AND LITERATURE REVIEW
    Gheith, Osama
    Alotaibi, Torki
    Alobiad, Khaled
    Nair, Prasad
    Zeineldein, Sohair
    Mahmoud, Tarek
    Halim, Medhat A.
    Aboatya, Hasaneen
    Balaha, Mohamed
    Atya, Khaled
    Nagib, Ayman Maher
    Alhatmi, Abdullah
    Sadon, Amal
    Meis, Jacques
    Zahab, Mohamed
    TRANSPLANT INTERNATIONAL, 2021, 34 : 365 - 365
  • [29] Case report: Disseminated Scedosporium apiospermum infection with invasive right atrial mass in a heart transplant patient
    Bourlond, Baudouin
    Cipriano, Ana
    Regamey, Julien
    Papadimitriou-Olivgeris, Matthaios
    Kamani, Christel
    Seidel, Danila
    Lamoth, Frederic
    Muller, Olivier
    Yerly, Patrick
    FRONTIERS IN CARDIOVASCULAR MEDICINE, 2022, 9
  • [30] Disseminated fusarium infection after allogeneic hematopoietic stem cell transplantation after CART A case report
    Fei, Hairong
    Liu, Xiaodan
    Sun, Lingjie
    Shi, Xue
    Wang, Wei
    Zhao, Hongguo
    Zhao, Chunting
    MEDICINE, 2022, 101 (45) : E31594