Efficient Electrochemical Sensor for Glucose Detection Based on Self-Supporting Electrode of Graphene Doped CuMOF/Cu(OH)2 Nanorod Arrays

A novel electrochemical sensor based on ternary nanocomposite of GE-CuMOF/Cu(OH)2 were prepared for detection of glucose. By a simple solvent method, Cu(OH)2 nanorod arrays were firstly in-situ grown on copper foam (CF), and then, by using 1,3,5-benzenetricarboxylic acid as ligand, CuMOF/Cu(OH)2 nano arrays doped with graphene (GE) nanosheets were prepared through a facile one-step hydrothermal method, and the resulted nanocomposite was noted as GE-CuMOF/Cu(OH)2@CF. The obtained GE-CuMOF/Cu(OH)2@CF sensor was characterized by scanning electron micrographs, X-ray diffraction, infrared spectroscopy and X-ray photoelectron spectroscopy. The GE-CuMOF/Cu(OH)2@CF electrode exhibited enhanced electrochemical activity for glucose oxide reaction. For glucose detection, the as-prepared sensor exhibited a low detection limit (0.3 mu mol/L), a wide linear concentration rang (0.001 to 0.597 mmol/L and 0.597 to 2.847 mmol/L), and high selectivity and stability. It was successfully applied to the detection of glucose in real human serum samples with recoveries of 97.3%-104.5%, suggesting that the GE-CuMOF/Cu(OH)2@CF electrode was a promising sensor to detect glucose in real samples.