An updated review of feline coronavirus: mind the two biotypes

被引:48
作者
Gao, Yong-Yu [1 ]
Wang, Qian [2 ]
Liang, Xiang-Yu [1 ]
Zhang, Shuang [1 ]
Bao, Di [1 ]
Zhao, Han [1 ]
Li, Shao-Bai [1 ]
Wang, Kai [1 ]
Hu, Gui-Xue [1 ]
Gao, Feng-Shan [3 ,4 ]
机构
[1] Jilin Agr Univ, Coll Anim Med, Dept Prevent Vet Med, Xincheng St 2888, Changchun 130118, Jilin, Peoples R China
[2] Changchun Univ Chinese Med, Affiliated Hosp, Changchun 130117, Jilin, Peoples R China
[3] Dalian Univ, Coll Life & Hlth Technol, Dept Bioengn, Xuefu St 10, Dalian 116622, Liaoning, Peoples R China
[4] Dalian Gene & Prot Engn Drug Screening Key Lab, Dalian 116622, Peoples R China
关键词
Feline coronavirus; Feline infectious peritonitis virus; Feline enteric coronavirus; Pathogenicity; Etiological characteristics; INFECTIOUS PERITONITIS VIRUS; ANTIBODY-DEPENDENT ENHANCEMENT; POLYMERASE-CHAIN-REACTION; ENTERIC CORONAVIRUS; SPIKE PROTEIN; RISK-FACTORS; DIAGNOSTIC-ACCURACY; MUTATION ANALYSIS; LEUKEMIA-VIRUS; CATS;
D O I
10.1016/j.virusres.2023.199059
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Feline coronavirus (FCoV) includes two biotypes: feline infectious peritonitis virus (FIPV) and feline enteric coronavirus (FECV). Although both biotypes can infect cats, their pathogenicities differ. The FIPV biotype is more virulent than the FECV biotype and can cause peritonitis or even death in cats, while most FECV biotypes do not cause lesions. Even pathogenic strains of the FECV biotype can cause only mild enteritis because of their very low virulence. This article reviews recent progress in FCoV research with regard to FCoV etiological characteristics; epidemiology; clinical symptoms and pathological changes; pathogenesis; and current diagnosis, prevention and treatment methods. It is hoped that this review will provide a reference for further research on FCoV and other coronaviruses.
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页数:12
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