Lodopyridones D - G from a marine-derived bacterium Saccharomonospora sp.

被引:2
作者
Hillman, Prima F. [1 ]
Lee, Ji Young [1 ]
Lee, Juri [1 ]
Lee, Jihye [1 ,2 ]
Oh, Dong-Chan [3 ]
Fenical, William [4 ]
Nam, Sang-Jip [1 ]
机构
[1] Ewha Womans Univ, Dept Chem & Nanosci, Seoul, South Korea
[2] REDONE SEOUL, Labs Marine New Drugs, Seoul, South Korea
[3] Seoul Natl Univ, Nat Prod Res Inst, Coll Pharm, Seoul, South Korea
[4] Univ Calif San Diego, Scripps Inst Oceanog, Ctr Marine Biotechnol & Biomed, La Jolla, CA USA
基金
新加坡国家研究基金会;
关键词
Saccharomonospora sp; marine-derived bacterium; lodopyridones D - G; HPLC-UV guided fractionation; METABOLITES;
D O I
10.1080/14786419.2023.2173192
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The intensive investigation of chemical components from the culture broth of the bacterium Saccharomonospora sp. CNQ-490 has yielded four new natural products, lodopyridones D - G (1 - 4) along with the previously reported compounds, lodopyridones A - C (5 - 7) and cotteslosin A (8). The planar structures of the lodopyridones D - G (1 - 4) were elucidated by interpreting the mass spectrometry, ultraviolet (UV) spectroscopy, and 1D and 2D nuclear magnetic spectroscopy (NMR) data, as well as comparing NMR data with those of the lodopyridones A - C (5 - 7).
引用
收藏
页码:2357 / 2362
页数:6
相关论文
共 21 条
[1]   Induction of Secondary Metabolites from the Marine-Derived Fungus Aspergillus versicolor through Co-cultivation with Bacillus subtilis [J].
Abdel-Wahab, Nada M. ;
Scharf, Sebastian ;
Ozkaya, Ferhat C. ;
Kurtan, Tibor ;
Mandi, Attila ;
Fouad, Mostafa A. ;
Kamel, Mohamed S. ;
Mueller, Werner E. G. ;
Kalscheuer, Rainer ;
Lin, Wenhan ;
Daletos, Georgios ;
Ebrahim, Weaam ;
Liu, Zhen ;
Proksch, Peter .
PLANTA MEDICA, 2019, 85 (06) :503-512
[2]   Bioactive microbial metabolites -: A personal view [J].
Bérdy, J .
JOURNAL OF ANTIBIOTICS, 2005, 58 (01) :1-26
[3]   Marine natural products [J].
Blunt, John W. ;
Copp, Brent R. ;
Hu, Wan-Ping ;
Munro, Murray H. G. ;
Northcote, Peter T. ;
Prinsep, Michele R. .
NATURAL PRODUCT REPORTS, 2007, 24 (01) :31-86
[4]   Cottoquinazoline A and Cotteslosins A and B, Metabolites from an Australian Marine-Derived Strain of Aspergillus versicolor [J].
Fremlin, Leith J. ;
Piggott, Andrew M. ;
Lacey, Ernest ;
Capon, Robert. J. .
JOURNAL OF NATURAL PRODUCTS, 2009, 72 (04) :666-670
[5]   Saccharobisindole, Neoasterric Methyl Ester, and 7-Chloro-4(1H)-quinolone: Three New Compounds Isolated from the Marine Bacterium Saccharomonospora sp. [J].
Kim, Sohee ;
Le, Tu Cam ;
Han, Sang-Ah ;
Hillman, Prima F. ;
Hong, Ahreum ;
Hwang, Sunghoon ;
Du, Young Eun ;
Kim, Hiyoung ;
Oh, Dong-Chan ;
Cha, Sun-Shin ;
Lee, Jihye ;
Nam, Sang-Jip ;
Fenical, William .
MARINE DRUGS, 2022, 20 (01)
[6]   Saccharoquinoline, a Cytotoxic Alkaloidal Meroterpenoid from Marine-Derived Bacterium Saccharomonospora sp. [J].
Le, Tu Cam ;
Lee, Eun Ju ;
Lee, Jihye ;
Hong, Ahreum ;
Yim, Chae-Yoon ;
Yang, Inho ;
Choi, Hyukjae ;
Chin, Jungwook ;
Cho, Sung Jin ;
Ko, Jaeyoung ;
Hwang, Hayoung ;
Nam, Sang-Jip ;
Fenical, William .
MARINE DRUGS, 2019, 17 (02)
[7]   Lodopyridones B and C from a marine sediment-derived bacterium Saccharomonospora sp. [J].
Le, Tu Cam ;
Yim, Chae-Yoon ;
Park, Songhee ;
Katila, Nikita ;
Yang, Inho ;
Song, Myoung Chong ;
Yoon, Yeo Joon ;
Choi, Dong-Young ;
Choi, Hyukjae ;
Nam, Sang-Jip ;
Fenical, William .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 27 (14) :3123-3126
[8]   Biosynthesis of l-4-Chlorokynurenine, an Antidepressant Prodrug and a Non-Proteinogenic Amino Acid Found in Lipopeptide Antibiotics [J].
Luhavaya, Hanna ;
Sigrist, Renata ;
Chekan, Jonathan R. ;
McKinnie, Shaun M. K. ;
Moore, Bradley S. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 58 (25) :8394-8399
[9]   Lodopyridone, a Structurally Unprecedented Alkaloid from a Marine Actinomycete [J].
Maloney, Katherine N. ;
MacMillan, John B. ;
Kauffman, Christopher A. ;
Jensen, Paul R. ;
DiPasquale, Antonio G. ;
Rheingold, Arnold L. ;
Fenical, William .
ORGANIC LETTERS, 2009, 11 (23) :5422-5424
[10]  
NONOMURA H, 1971, J FERMENT TECHNOL, V49, P895