Initial Staging and Response Evaluation With 18F-FDG PET/CT in a Rare Case of Nested Variant Urothelial Urethral Cancer

Primary urothelial urethral cancer is a relatively infrequent but serious form of cancer in the urinary tract, and nested variant is extremely rare. Until now, no studies have been published regarding F-18-FDG PET/CT in patients with primary urothelial urethral cancer. In this study, we discussed the role of F-18-FDG PET/CT in the initial staging, treatment response evaluation, and recurrence assessment of a 53-year-old woman with nested variant urothelial urethral cancer, which could lead to timely diagnosis and evaluation of the extent of involvement, thus achieving the best treatment plan for this group of patients.