Design and applications of carbon dots-based ratiometric fluorescent probes: A review

被引:108
作者
Chen, Bin-Bin [1 ,2 ]
Liu, Meng-Li [3 ,4 ]
Gao, Ya-Ting [1 ]
Chang, Shuai [1 ]
Qian, Ruo-Can [1 ]
Li, Da-Wei [1 ]
机构
[1] East China Univ Sci & Technol, Frontiers Sci Ctr Materiobiol & Dynam Chem, Sch Chem & Mol Engn, Key Lab Adv Mat,Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China
[2] Chinese Univ Hong Kong, Sch Sci & Engn, Shenzhen Inst Aggregate Sci & Technol, Shenzhen 518172, Peoples R China
[3] Fudan Univ, Coll Chem & Mat, Dept Chem, Lab Adv Mat,Shanghai Key Lab Mol Catalysis & Inno, Shanghai 200433, Peoples R China
[4] Fudan Univ, Coll Chem & Mat, State Key Lab Mol Engn Polymers, Shanghai 200433, Peoples R China
基金
中国国家自然科学基金;
关键词
carbon dots; ratiometric fluorescent probes; construction strategy; sensing type; a review; GRAPHENE-QUANTUM-DOTS; METAL-ORGANIC FRAMEWORKS; HIGHLY SELECTIVE DETECTION; DUAL-EMISSION PROBE; ONE-POT SYNTHESIS; SENSITIVE DETECTION; LABEL-FREE; SILICA NANOPARTICLES; GOLD NANOCLUSTERS; FACILE SYNTHESIS;
D O I
10.1007/s12274-022-4840-2
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Ratiometric fluorescence (FL) probes can eliminate the background interference and provide more accurate detection results than single emission intensity-based nanoprobes. Recently, carbon dots (CDs)-based ratiometric FL probes have received extensive research attention due to their excellent biocompatibility, water solubility, and multi-emission capabilities. In this review, we firstly summarize the construction strategies of CDs-based ratiometric FL probes, including physical mixing, nanohybrid, and dual-emitting CDs strategies. Additionally, we classify the sensing types of CDs-based ratiometric FL probes into five categories according to the difference in spectral variation caused by analytes: "single-response-ON", "single-response-OFF", "double-responses-ON", "double-responses-OFF", and "double-responses-Reverse" types. Finally, a thorough overview of CDs-based ratiometric FL probe applications in ions, molecules, pH, and temperature sensing is provided. We believe this review can show the latest research progress of CDs-based ratiometric FL sensing fields and provide perspectives on future developments for the construction of CDs-based ratiometric FL probes and their potential applications.
引用
收藏
页码:1064 / 1083
页数:20
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