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Evaluation of mechanical and biological properties of akermanite/poly-ether-ether-ketone composite fabricated by high-temperature laser powder bed fusion
被引:2
|作者:
Chen, Zhiyuan
[1
]
Wang, Haoze
[1
]
Su, Jin
[1
]
Shu, Zixing
[2
]
Hou, Jiayi
[1
]
Chen, Peng
[1
]
Li, Zhaoqing
[3
]
Yan, Chunze
[1
]
Shi, Yusheng
[1
]
机构:
[1] Huazhong Univ Sci & Technol, Sch Mat Sci & Engn, State Key Lab Mat Proc & Die & Mould Technol, Wuhan 430074, Peoples R China
[2] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Orthoped Surg, Wuhan 430030, Peoples R China
[3] Wuhan Zeqing Technol Co Ltd, Wuhan 430074, Peoples R China
基金:
中国博士后科学基金;
中国国家自然科学基金;
关键词:
Additive manufacturing;
Laser powder bed fusion;
Akermanite;
poly-ether-ether-ketone composite;
Mechanical properties;
Biological properties;
IN-VIVO EVALUATION;
PEEK;
PROCESSABILITY;
NANOCOMPOSITE;
BIOCERAMICS;
BIOACTIVITY;
SCAFFOLDS;
D O I:
10.18063/ijb.699
中图分类号:
R318 [生物医学工程];
学科分类号:
0831 ;
摘要:
High-temperature laser bed powder fusion (HT-LPBF) technology is an ideal method for processing poly-ether-ether-ketone (PEEK) implants with personalized bionic structures, but the biological inertia of PEEK limits its medical applications. In this study, we evaluated the mechanical and biological properties of a novel akermanite (AKM)/PEEK composite for HT-LPBF. The results showed that tiny AKM particles are evenly attached to the surface of the PEEK particle. The delayed peak crystallization temperature and stable sintering window ensure the processing feasibility of the AKM/PEEK composites. The tensile strength and Young's modulus are in the range of 30.83-98.73 MPa and 2.27-3.71 GPa, respectively, which can match the properties of cancellous bones and meet their implanting requirement. The CCK-8 experiments demonstrated the biocompatibility of the composites and the good proliferation of bone marrow stromal cells. The dense hydroxyapatite network layer and petal-like hydroxyapatite demonstrates biological activity, indicating that the composite has a good potential in the orthopedics fields.
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页数:14
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