Sex differences in the effects of sleep disorders on cognitive dysfunction

被引:27
作者
Zhou, Lv [1 ]
Kong, Jingting [1 ]
Li, Xiaoli [1 ,2 ]
Ren, Qingguo [1 ,2 ,3 ]
机构
[1] Southeast Univ, Sch Med, Nanjing 210009, Peoples R China
[2] Southeast Univ, Affiliated ZhongDa Hosp, Dept Neurol, Nanjing 210009, Peoples R China
[3] Southeast Univ, Affiliated ZhongDa Hosp, Sch Med, Dept Neurol, 87 Dingjiaqiao, Nanjing 210009, Jiangsu, Peoples R China
基金
中国国家自然科学基金;
关键词
Sex differences; Sleep disorders; Cognitive dysfunction; Mechanisms; SELF-REPORTED SLEEP; GENDER-DIFFERENCES; ALZHEIMERS-DISEASE; INCIDENT DEMENTIA; BRAIN ACTIVITY; IMPAIRMENT; INSOMNIA; DEPRIVATION; MEMORY; MELATONIN;
D O I
10.1016/j.neubiorev.2023.105067
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Sleep is an essential physiological function that sustains human life. Sleep disorders involve problems with the quality, duration, and abnormal behaviour of sleep. Insomnia is the most common sleep disorder, followed by sleep-disordered breathing (SDB). Sleep disorders often occur along with medical conditions or other mental health conditions. Of particular interest to researchers is the role of sleep disorders in cognitive dysfunction. Sleep disorder is a risk factor for cognitive dysfunction, yet the exact pathogenesis is still far from agreement. Little is known about how sex differences influence the changes in cognitive functions caused by sleep disorders. This narrative review examines how sleep disorders might affect cognitive impairment, and then explores the sex-specific consequences of sleep disorders as a risk factor for dementia and the potential underlying mechanisms. Some insights on the direction of further research are also presented.
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页数:10
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