Safe and effective treatments are needed for cryptosporidiosis, a truly neglected tropical disease

被引:18
作者
Gilbert, Ian H. [1 ]
Vinayak, Sumiti [2 ]
Striepen, Boris [3 ]
Manjunatha, Ujjini H. [4 ]
Khalil, Ibrahim A. [5 ]
Van Voorhis, Wesley C. [6 ]
机构
[1] Univ Dundee, DDU, Dundee, Scotland
[2] Univ Illinois, Coll Vet Med, Dept Pathobiol, Urbana, IL USA
[3] Univ Penn, Sch Vet Med, Dept Pathobiol, Philadelphia, PA USA
[4] Novartis Inst Biomed Res Inc, Global Hlth, Emeryville, CA USA
[5] State Washington, Dept Hlth, Seattle, WA USA
[6] Univ Washington, Div AID, Med, Seattle, WA 98195 USA
来源
BMJ GLOBAL HEALTH | 2023年 / 8卷 / 08期
关键词
Parasitology; Child health; BUMPED-KINASE INHIBITORS; CHILDREN; INFECTION; ETIOLOGY; DIARRHEA; PARVUM; MORBIDITY; MORTALITY; BURDEN; LEAD;
D O I
10.1136/bmjgh-2023-012540
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
引用
收藏
页数:6
相关论文
共 54 条
  • [1] Treatment of cryptosporidiosis in immunocompromised individuals: systematic review and meta-analysis
    Abubakar, I.
    Aliyu, S. H.
    Arumugam, C.
    Usman, N. K.
    Hunter, P. R.
    [J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2007, 63 (04) : 387 - 393
  • [2] Effect of nitazoxanide on morbidity and mortality in Zambian children with cryptosporidiosis: a randomised controlled trial
    Amadi, B
    Mwiya, M
    Musuku, J
    Watuka, A
    Sianongo, S
    Ayoub, A
    Kelly, P
    [J]. LANCET, 2002, 360 (9343) : 1375 - 1380
  • [3] High dose prolonged treatment with nitazoxanide is not effective for cryptosporidiosis in HIV positive Zambian children: a randomised controlled trial
    Amadi, Beatrice
    Mwiya, Mwiya
    Sianongo, Sandie
    Payne, Lara
    Watuka, Angela
    Katubulushi, Max
    Kelly, Paul
    [J]. BMC INFECTIOUS DISEASES, 2009, 9
  • [4] Amoo John Kehinde, 2018, Pan Afr Med J, V30, P66, DOI 10.11604/pamj.2018.30.66.13160
  • [5] Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection
    Arnold, Samuel L. M.
    Choi, Ryan
    Hulverson, Matthew A.
    Schaefer, Deborah A.
    Vinayak, Sumiti
    Vidadala, Rama S. R.
    McCloskey, Molly C.
    Whitman, Grant R.
    Huang, Wenlin
    Barrett, Lynn K.
    Ojo, Kayode K.
    Fan, Erkang
    Maly, Dustin J.
    Riggs, Michael W.
    Striepen, Boris
    Van Voorhis, Wesley C.
    [J]. JOURNAL OF INFECTIOUS DISEASES, 2017, 216 (01) : 55 - 63
  • [6] Use-case scenarios for an anti-Cryptosporidium therapeutic
    Ashigbie, Paul G.
    Shepherd, Susan
    Steiner, Kevin L.
    Amadi, Beatrice
    Aziz, Natasha
    Manjunatha, Ujjini H.
    Spector, Jonathan M.
    Diagana, Thierry T.
    Kelly, Paul
    [J]. PLOS NEGLECTED TROPICAL DISEASES, 2021, 15 (03):
  • [7] Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis
    Baragana, Beatriz
    Forte, Barbara
    Choi, Ryan
    Hewitt, Stephen Nakazawa
    Bueren-Calabuig, Juan A.
    Pisco, Joao Pedro
    Peet, Caroline
    Dranow, David M.
    Robinson, David A.
    Jansen, Chimed
    Norcross, Neil R.
    Vinayak, Sumiti
    Anderson, Mark
    Brooks, Carrie F.
    Cooper, Caitlin A.
    Damerow, Sebastian
    Delves, Michael
    Dowers, Karen
    Duffy, James
    Edwards, Thomas E.
    Hallyburton, Irene
    Horst, BenjaminG.
    Hulverson, Matthew A.
    Ferguson, Liam
    Belen Jimenez-Diaz, Maria
    Jumani, Rajiv S.
    Lorimer, Donald D.
    Love, Melissa S.
    Maher, Steven
    Matthews, Holly
    McNamara, Casew.
    Miller, Peter
    O'Neill, Sandra
    Ojo, Kayode K.
    Osuna-Cabello, Maria
    Pinto, Erika
    Post, John
    Riley, Jennifer
    Rottmann, Matthias
    Sanz, Laura M.
    Scullion, Paul
    Sharma, Arvind
    Shepherd, Sharon M.
    Shishikura, Yoko
    Simeons, Frederick R. C.
    Stebbins, Erin E.
    Stojanovski, Laste
    Straschil, Ursula
    Tamaki, Fabio K.
    Tamjar, Jevgenia
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (14) : 7015 - 7020
  • [8] Target Identification of an Antimalarial Oxaborole Identifies AN13762 as an Alternative Chemotype for Targeting CPSF3 in Apicomplexan Parasites
    Bellini, Valeria
    Swale, Christopher
    Brenier-Pinchart, Marie-Pierre
    Pezier, Tiffany
    Georgeault, Sonia
    Laurent, Fabrice
    Hakimi, Mohamed-Ali
    Bougdour, Alexandre
    [J]. ISCIENCE, 2020, 23 (12)
  • [9] Performance of three rapid diagnostic tests for the detection of Cryptosporidium spp. and Giardia duodenalis in children with severe acute malnutrition and diarrhoea
    Bitilinyu-Bangoh, Joseph
    Voskuijl, Wieger
    Thitiri, Johnstone
    Menting, Sandra
    Verhaar, Nienke
    Mwalekwa, Laura
    de Jong, Daisy B.
    van Loenen, Merlin
    Mens, Petra F.
    Berkley, James A.
    Bandsma, Robert H. J.
    Schallig, Henk D. F. H.
    [J]. INFECTIOUS DISEASES OF POVERTY, 2019, 8 (01)
  • [10] Optimization of Methionyl tRNA-Synthetase Inhibitors for Treatment of Cryptosporidium Infection
    Buckner, Frederick S.
    Ranade, Ranae M.
    Gillespie, J. Robert
    Shibata, Sayaka
    Hulverson, Matthew A.
    Zhang, Zhongsheng
    Huang, Wenlin
    Choi, Ryan
    Verlinde, Christophe L. M. J.
    Hol, Wim G. J.
    Ochida, Atsuko
    Akao, Yuichiro
    Choy, Robert K. M.
    Van Voorhis, Wesley C.
    Arnold, Sam L. M.
    Jumani, Rajiv S.
    Huston, Christopher D.
    Fan, Erkang
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2019, 63 (04)