Programmable, high-speed, adaptive optics partially confocal multi-spot ophthalmoscope using a digital micromirror device

被引：7

作者：

Lee, Soohyun ^{[1
]}

Choi, Stacey S. ^{[1
,2
]}

Meleppat, Ratheesh K. ^{[3
,4
]}

Zawadzki, Robert J. ^{[3
,4
]}

Doble, Nathan ^{[1
,2
]}

机构：

[1] Ohio State Univ, Coll Optometry, 338 West 10th Ave, Columbus, OH 43210 USA

[2] Ohio State Univ, Havener Eye Inst, Dept Ophthalmol & Visual Sci, 915 Olentangy River Rd Suite 5000, Wright Patterson AFB, OH 43212 USA

[3] Univ Calif Sacramento, UC Davis Eye Ctr, Dept Ophthalmol & Vis Sci, Davis, 4860 Y St, Suite 2400, Sacramento, CA 95817 USA

[4] Univ Calif Davis, Dept Cell Biol & Human Anat, UC Davis EyePod Small Anim Ocular Imaging Lab, 4320 Tupper Hall, Davis, CA 95616 USA

来源：

OPTICS LETTERS | 2023年 / 48卷 / 03期

基金：

美国国家卫生研究院;

关键词：

Cameras; -; Ophthalmology;

D O I：

10.1364/OL.480688

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

A high-speed, adaptive optics partially confocal multi-spot ophthalmoscope (AO-pcMSO) using a digital micromirror device (DMD) in the illumination channel and a fast 2D CMOS camera is described. The camera is synchronized with the DMD allowing projection of multiple, simultaneous AO-corrected spots onto the human retina. Spatial filtering on each raw retinal image before reconstruction works as an array virtual pinholes. A frame acquisition rate of 250 fps is achieved by applying this parallel projection scheme. The contrast improves by 2-3 fold when compared to a standard flood illumination architecture. Partially confocal images of the human retina show cone and rod photoreceptors over a range of retinal eccentricities. & COPY; 2023 Optica Publishing Group

引用

页码：791 / 794

页数：4

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