REGRESSION ANALYSIS OF PANEL COUNT DATA WITH BOTH TIME-DEPENDENT COVARIATES AND TIME-VARYING EFFECTS

Panel count data occur in many fields, including clinical, demographic, and industrial studies, and an extensive body of literature has been established for their regression analysis. However, most existing methods apply only to situations in which both the covariates and their effects are constant or one of them may be time dependent. This study considers the situation in which both the covariates and their effects may be time dependent, and we develop an estimating equation -based approach to estimate these time-varying effects. The proposed method uses the B-splines to approximate the time-dependent coefficients, and we establish the asymptotic properties of the proposed estimators. To assess the finite-sample per-formance of the proposed estimators, we conduct an extensive simulation study, showing that the proposed method works well in practical situations. Lastly, we demonstrate our method by applying it to data from the China Health and Nutrition Survey.