Bacteriome and mycobiome dysbiosis in oral mucosal dysplasia and oral cancer

被引：11

作者：

Belibasakis, Georgios N. ^{[1
,5
]}

Senevirantne, Chaminda Jayampath ^{[2
]}

Jayasinghe, Ruwan Duminda ^{[3
]}

Vo, Phuc Thi-Duy ^{[4
]}

Bostanci, Nagihan ^{[1
]}

Choi, Youngnim ^{[4
]}

机构：

[1] Karolinska Inst, Dept Dent Med, Div Oral Dis, Stockholm, Sweden

[2] Univ Queensland, Sch Dent, Herston, Qld, Australia

[3] Univ Peradeniya, Fac Dent Sci, Dept Oral Med & Periodontol, Peradeniya, Sri Lanka

[4] Sch Dent, Dept Immunol & Mol Microbiol, Seoul, South Korea

[5] Karolinska Inst, Dept Dent Med, Alfred Nobels 8, S-14152 Huddinge, Sweden

来源：

PERIODONTOLOGY 2000 | 2024年 / 96卷 / 01期

关键词：

bacteriome; dysbiosis; microbiome; mycobiome; oral cancer; oral candidiasis; oral dysplasia; oral medicine; oral mucosa; oral pathology; SQUAMOUS-CELL CARCINOMA; FUSOBACTERIUM-NUCLEATUM; PORPHYROMONAS-GINGIVALIS; HELICOBACTER-PYLORI; PERIODONTAL-DISEASE; MICROBIOME; CAVITY; TRANSFORMATION; BIOGEOGRAPHY; ASSOCIATION;

D O I：

10.1111/prd.12558

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

It has long been considered that the oral microbiome is tightly connected to oral health and that dysbiotic changes can be detrimental to the occurrence and progression of dysplastic oral mucosal lesions or oral cancer. Improved understanding of the concepts of microbial dysbiosis together with advances in high-throughput molecular sequencing of these pathologies have charted in greater microbiological detail the nature of their clinical state. This review discusses the bacteriome and mycobiome associated with oral mucosal lesions, oral candidiasis, and oral squamous cell carcinoma, aiming to delineate the information available to date in pursuit of advancing diagnostic and prognostic utilities for oral medicine.

引用

页码：95 / 111

页数：17

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