Cytoreductive Radical Prostatectomy for Metastatic Hormone-sensitive Prostate Cancer-Evidence from Recent Prospective Reports

被引:21
作者
Rajwa, Pawel [1 ,2 ]
Zattoni, Fabio [3 ]
Maggi, Martina [4 ]
Marra, Giancarlo [5 ]
Kroyer, Petra [1 ]
Shariat, Shahrokh F. [1 ,6 ,7 ,8 ]
Briganti, Alberto [9 ]
Montorsi, Francesco [9 ]
Heidegger, Isabel [10 ]
Gandaglia, Giorgio [9 ]
机构
[1] Med Univ Vienna, Dept Urol, Vienna, Austria
[2] Med Univ Silesia, Dept Urol, Zabrze, Poland
[3] Univ Padua, Dept Surg Oncol & Gastroenterol, Urol Unit, Padua, Italy
[4] Sapienza Rome Univ, Policlin Umberto I Hosp, Dept Maternal Infant & Urol Sci, Rome, Italy
[5] Univ Torino, San Giovanni Battista Hosp, Dept Urol, Turin, Italy
[6] Charles Univ Prague, Fac Med 2, Dept Urol, Prague, Czech Republic
[7] Weill Cornell Med Coll, Dept Urol, New York, NY USA
[8] Univ Texas Southwestern, Dept Urol, Dallas, TX USA
[9] IRCCS Osped San Raffaele, Div Oncol, Unit Urol, URI, Milan, Italy
[10] Med Univ Innsbruck, Dept Urol, Innsbruck, Austria
关键词
Radical prostatectomy; Cytoreductive; Prostate cancer; Oligometastatic; Metastatic; LOCAL TREATMENT;
D O I
10.1016/j.euf.2023.01.011
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Cytoreductive radical prostatectomy (cRP) is currently tested in patients with low -volume metastatic hormone-sensitive prostate cancer (mHSPC). We aimed to review the literature and to report recent prospective studies addressing oncologic and func-tional results of cRP in mHSPC patients. Based on prospective data, we found that cRP is feasible and provides favorable oncologic outcomes when compared with systemic therapy alone in well-selected patients with low-volume mHSPC. Furthermore, cRP has beneficial effects on local disease control in mHSPC with an acceptable rate of adverse events.Patient summary: In the present study, we reviewed recent prospective studies analyz-ing the survival and safety of prostate surgical excision in patients with mHSPC. We have found that prostate surgical excision is a feasible, safe, and potentially effective therapy in selected patients with mHSPC.(c) 2023 European Association of Urology. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:637 / 641
页数:5
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