The Beneficial Roles of Sargassum spp. in Skin Disorders

被引：2

作者：

Lee, Min-Kyeong ^{[1
,3
]}

Jeong, Hyeon Hak ^{[2
]}

Kim, Myeong-Jin ^{[1
]}

Seo, Jae Seong ^{[2
]}

Hwang, Ji Young ^{[2
]}

Jung, Won-Kyo ^{[4
,5
]}

Moon, Kyoung Mi ^{[1
]}

Lee, Incheol ^{[6
]}

Lee, Bonggi ^{[1
,2
]}

机构：

[1] Pukyong Natl Univ, Dept Food Sci & Nutr, 599-1 Daeyeondong Namgu, Busan 48513, South Korea

[2] Pukyong Natl Univ, Dept Smart Green Technol Engn, Busan, South Korea

[3] Natl Inst Fisheries Sci, Biotechnol Res Div, Busan, South Korea

[4] Pukyong Natl Univ, Div Biomed Engn, Busan, South Korea

[5] Pukyong Natl Univ, Res Ctr Marine Integrated Bion Technol, Busan, South Korea

[6] Pukyong Natl Univ, Dept Ocean Engn, Busan, South Korea

来源：

JOURNAL OF MEDICINAL FOOD | 2024年 / 27卷 / 04期

基金：

新加坡国家研究基金会;

关键词：

brown seaweed; cosmeceutical; pharmaceutical; Sargassum; skin disorders; SEAWEED SARGASSUM; IN-VITRO; MECHANISMS; EXTRACT; APO-9'-FUCOXANTHINONE; RESPONSES; MELANOMA; MUTICUM; CELLS; MICE;

D O I：

10.1089/jmf.2023.K.0160

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

As the body's largest organ, the skin is located at the internal and external environment interface, serving as a line of defense against various harmful stressors. Recently, marine-derived physiologically active ingredients have attracted considerable attention in the cosmeceutical industry due to their beneficial effects on skin health. Sargassum, a genus of brown macroalgae, has traditionally been consumed as food and medicine in several countries and is rich in bioactive compounds such as meroterpenoids, sulfated polysaccharides, fucoidan, fucoxanthin, flavonoids, and terpenoids. Sargassum spp. have various beneficial effects on skin disorders. They help with atopic dermatitis by improving skin barrier protection and reducing inflammation. Several species show potential in treating acne by inhibiting bacterial growth and reducing inflammation. Some species, such as Sargassum horneri, demonstrate antiallergic effects by modulating mast cell activity. Certain Sargassum species exhibit anticancer activity by inhibiting tumor growth and promoting apoptosis, and some species help with wound healing by promoting angiogenesis and reducing oxidative stress. Overall, Sargassum spp. demonstrate potential for treating and managing various skin conditions. Therefore, the bioactive compounds of Sargassum spp. may be natural ingredients with a wide range of functional properties for preventing and treating skin disorders. The present review focused on the various biological effects of Sargassum extracts and derived compounds on skin disorders.

引用

页码：359 / 368

页数：10

共 61 条

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