Application of Advanced Technologies-Nanotechnology, Genomics Technology, and 3D Printing Technology-In Precision Anesthesia: A Comprehensive Narrative Review

被引：12

作者：

Gu, Shiyao ^{[1
]}

Luo, Qingyong ^{[1
]}

Wen, Cen ^{[1
]}

Zhang, Yu ^{[2
]}

Liu, Li ^{[2
]}

Liu, Liu ^{[1
]}

Liu, Su ^{[3
]}

Chen, Chunhua ^{[4
]}

Lei, Qian ^{[1
]}

Zeng, Si ^{[1
]}

机构：

[1] Univ Elect Sci & Technol China, Sichuan Prov Peoples Hosp, Sch Med, Dept Anesthesiol, Chengdu 610072, Peoples R China

[2] Chengdu Univ Tradit Chinese Med, Sch Med & Life Sci, Chengdu 610072, Peoples R China

[3] Xuzhou Med Univ, Dept Anesthesiol, Affiliated Hosp, Xuzhou 221000, Peoples R China

[4] Peking Univ Hlth Sci Ctr, Sch Basic Med Sci, Dept Anat & Embryol, Beijing 100191, Peoples R China

来源：

PHARMACEUTICS | 2023年 / 15卷 / 09期

基金：

中国国家自然科学基金;

关键词：

anesthesia; algology; 3D printing; nanotechnology; genomics; precision medicine; anesthetic safety; INTRAVENOUS REGIONAL ANESTHESIA; LIPOSOME-ASSOCIATED BUPIVACAINE; NANOSTRUCTURED LIPID CARRIERS; DRUG-DELIVERY SYSTEMS; GENE POLYMORPHISMS; CYP2C19; GENOTYPE; LOW-COST; PLASMA-CONCENTRATIONS; OXIDE NANOPARTICLES; ANALGESIC THERAPY;

D O I：

10.3390/pharmaceutics15092289

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

There has been increasing interest and rapid developments in precision medicine, which is a new medical concept and model based on individualized medicine with the joint application of genomics, bioinformatics engineering, and big data science. By applying numerous emerging medical frontier technologies, precision medicine could allow individualized and precise treatment for specific diseases and patients. This article reviews the application and progress of advanced technologies in the anesthesiology field, in which nanotechnology and genomics can provide more personalized anesthesia protocols, while 3D printing can yield more patient-friendly anesthesia supplies and technical training materials to improve the accuracy and efficiency of decision-making in anesthesiology. The objective of this manuscript is to analyze the recent scientific evidence on the application of nanotechnology in anesthesiology. It specifically focuses on nanomedicine, precision medicine, and clinical anesthesia. In addition, it also includes genomics and 3D printing. By studying the current research and advancements in these advanced technologies, this review aims to provide a deeper understanding of the potential impact of these advanced technologies on improving anesthesia techniques, personalized pain management, and advancing precision medicine in the field of anesthesia.

引用

页数：27

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