Opposing Roles of Thymus-Derived Foxp3+Regulatory T Cells in the Control of Beta Cell Autoimmunity and Adipose Tissue Homeostasis

被引:0
|
作者
Yilmazer, Kirgin A. [1 ]
Zevla, D. [1 ]
Eugster, A. [2 ]
Boernert, M. [1 ]
Malmkvist, R. [1 ]
Voehringer, D. [3 ,4 ]
Liston, A. [5 ,6 ]
Chavakis, T. [7 ,8 ]
Bonifacio, E. [2 ,9 ,10 ,11 ]
Chatzigeorgiou, A. [7 ,8 ]
Schlenner, S. [5 ]
Kretschmer, K. [1 ,9 ,10 ,11 ]
机构
[1] Tech Univ Dresden, Ctr Regenerat Therapies Dresden CRTD, Ctr Mol & Cellular Bioengn CMCB, Mol & Cellular Immunol Immune Regulat, D-01307 Dresden, Germany
[2] Tech Univ Dresden, Ctr Mol & Cellular Bioengn CMCB, Regenerat Therapies Diabet, DFG Ctr Regenerat Therapies Dresden CRTD, D-01307 Dresden, Germany
[3] Friedrich Alexander Univ Erlangen Nurnberg FAU, Inst Clin Microbiol, Div Infect Biol, D-91054 Erlangen, Germany
[4] Univ Klinikum Erlangen, D-91054 Erlangen, Germany
[5] Univ Leuven, KU Leuven, Dept Microbiol Immunol & Transplantat, B-3000 Leuven, Belgium
[6] Babraham Inst, Lab Lymphocyte Signalling & Dev, Cambridge CB22 3AT, England
[7] Tech Univ Dresden, Inst Clin Chem, Fac Med, D-01307 Dresden, Germany
[8] Tech Univ Dresden, Lab Med, Fac Med, D-01307 Dresden, Germany
[9] Univ Hosp, Paul Langerhans Inst Dresden PLID, Helmholtz Zentrum Munchen, Fetscherstr 74, D-01307 Dresden, Germany
[10] Tech Univ Dresden, Med Fac Carl Gustav Carus, Fetscherstr 74, D-01307 Dresden, Germany
[11] German Ctr Diabet Res DZD, Ingolstadter Landstr 1, D-85764 Neuherberg, Germany
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
P118
引用
收藏
页码:112 / 112
页数:1
相关论文
共 50 条
  • [1] Distinct roles of Foxp3+regulatory T cell sublineages in adipose tissue homeostasis and obesity
    Kirgin, Acelya Yilmazer
    Boernert, Marie
    Voehringer, David
    Liston, Adrian
    Schlenner, Susan
    Kretschmer, Karsten
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2021, 51 : 50 - 50
  • [2] Homeostasis of thymus-derived naturally occurring Foxp3+regulatory T cells is controlled by ultraviolet B exposure in the skin
    Yamazaki, S.
    Nishioka, A.
    Kasuya, S.
    Taguchi, O.
    Morita, A.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2014, 134 : S114 - S114
  • [3] OPPOSING EFFECTS OF ALCOHOL ON FOXP3+REGULATORY T CELLS
    Lim, Y.
    Chandrasekaran, U.
    Love, R.
    Iwashima, M.
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2018, 42 : 103A - 103A
  • [4] Homeostasis of Thymus-Derived Foxp3+ Regulatory T Cells Is Controlled by Ultraviolet B Exposure in the Skin
    Yamazaki, Sayuri
    Nishioka, Akiko
    Kasuya, Saori
    Ohkura, Naganari
    Hemmi, Hiroaki
    Kaisho, Tsuneyasu
    Taguchi, Osamu
    Sakaguchi, Shimon
    Morita, Akimichi
    JOURNAL OF IMMUNOLOGY, 2014, 193 (11): : 5488 - 5497
  • [5] Adipose tissue macrophages induce PPARγ- high FOXP3+regulatory T cells
    Onodera, Toshiharu
    Fukuhara, Atsunori
    Jang, Myoung Ho
    Shin, Jihoon
    Aoi, Keita
    Kikuta, Junichi
    Otsuki, Michio
    Ishii, Masaru
    Shimomura, Iichiro
    SCIENTIFIC REPORTS, 2015, 5
  • [6] Induced and thymus-derived Foxp3+ regulatory T cells share a common niche
    Huang, Yi-Ju
    Haist, Verena
    Baumgaertner, Wolfgang
    Foehse, Lisa
    Prinz, Immo
    Suerbaum, Sebastian
    Floess, Stefan
    Huehn, Jochen
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2014, 44 (02) : 460 - 468
  • [7] Thymus-derived Foxp3+ regulatory T cells upregulate RORγt expression under inflammatory conditions
    Juhao Yang
    Mangge Zou
    Joern Pezoldt
    Xuyu Zhou
    Jochen Huehn
    Journal of Molecular Medicine, 2018, 96 : 1387 - 1394
  • [8] Thymus-derived Foxp3+ regulatory T cells upregulate RORt expression under inflammatory conditions
    Yang, Juhao
    Zou, Mangge
    Pezoldt, Joern
    Zhou, Xuyu
    Huehn, Jochen
    JOURNAL OF MOLECULAR MEDICINE-JMM, 2018, 96 (12): : 1387 - 1394
  • [9] Analysis of tissue specific mechanisms that control the maintenance of Foxp3+regulatory T cells in the intestine
    Morales, Elisa Cruz
    Hart, Andrew
    Laufer, Terri M.
    JOURNAL OF IMMUNOLOGY, 2020, 204 (01):
  • [10] Foxp3+regulatory T cell therapy for tolerance in autoimmunity and solid organ transplantation
    Sanders, Jes M.
    Jeyamogan, Shareni
    Mathew, James M.
    Leventhal, Joseph R.
    FRONTIERS IN IMMUNOLOGY, 2022, 13