A Review of Energy Modalities Used for Focal Therapy of Prostate Cancer

被引:4
作者
Tayebi, Shima [1 ]
Debnath, Neha [2 ]
Sidana, Abhinav [3 ]
机构
[1] Univ Cincinnati, Coll Med, Dept Radiol, Cincinnati, OH USA
[2] Icahn Sch Med Mt Sinai Morningside West, New York, NY USA
[3] Univ Chicago Med & Biol Sci, Dept Surg, Sect Urol, Chicago, IL 60637 USA
关键词
Prostate cancer; Focal therapy; Ablation; Recurrence; INTENSITY FOCUSED ULTRASOUND; PARTIAL GLAND ABLATION; INTERSTITIAL TUMOR ABLATION; LASER-ABLATION; IRREVERSIBLE ELECTROPORATION; PHOTOTHERMAL ABLATION; FUNCTIONAL OUTCOMES; THERMAL THERAPY; CRYOTHERAPY; TRIAL;
D O I
10.1007/s40137-023-00380-x
中图分类号
R61 [外科手术学];
学科分类号
摘要
Purpose of ReviewProstate cancer (PCa) is a prevalent cancer among men that needs effective treatment approaches. Traditionally, PCa was managed through whole-gland radical therapy or Active Surveillance. However, the field has witnessed a notable shift towards less invasive treatment options. Focal prostate ablation has emerged as a promising method for PCa treatment, using a range of energy modalities, each with its unique mechanism and proven efficacy in different settings. This review aims to discuss the different energy modalities used for focal therapy of prostate cancer, their mechanism of action, and clinical outcomes.Recent FindingsFocal therapy is a developing treatment option that involves focal treatment of PCa. Recent findings suggest Focal therapy for PCa shows well-tolerated and great oncological outcomes in localized prostate cancer while minimizing the side effects and damage to non-cancerous tissue. Currently, there are various modalities used for prostate cancer treatment, and new modalities are continually being introduced. Each modality has its advantages and disadvantages, and the selection of the appropriate method becomes important for improved treatment and cancer management. Familiarizing ourselves with these modalities, understanding their mechanisms, and recognizing their limitations can assist us in making more informed decisions regarding treatment methods for patients and achieving better outcomes.SummaryProstate focal therapy employs a variety of energy modalities, each with its own set of benefits and drawbacks, making certain modalities more suitable for specific groups of patients. Having a comprehensive understanding of these modalities, including their mechanisms, drawbacks, and limitations, is crucial and beneficial. Additionally, identifying the ideal candidates for each modality can significantly enhance treatment approaches and ultimately lead to improved outcomes.
引用
收藏
页码:331 / 346
页数:16
相关论文
共 95 条
[1]   High Intensity Focused Ultrasound Hemigland Ablation for Prostate Cancer: Initial Outcomes of a United States Series [J].
Abreu, Andre Luis ;
Peretsman, Samuel ;
Iwata, Atsuko ;
Shakir, Aliasger ;
Iwata, Tsuyoshi ;
Brooks, Jessica ;
Tafuri, Alessandro ;
Ashrafi, Akbar ;
Park, Daniel ;
Cacciamani, Giovanni E. ;
Kaneko, Masatomo ;
Duddalwar, Vinay ;
Aron, Manju ;
Palmer, Suzanne ;
Gill, Inderbir S. .
JOURNAL OF UROLOGY, 2020, 204 (04) :741-747
[2]   Contemporary treatments in prostate cancer focal therapy [J].
Ahdoot, Michael ;
Lebastchi, Amir H. ;
Turkbey, Baris ;
Wood, Bradford ;
Pinto, Peter A. .
CURRENT OPINION IN ONCOLOGY, 2019, 31 (03) :200-206
[3]   Focal Ablation Targeted to the Index Lesion in Multifocal Localised Prostate Cancer: a Prospective Development Study [J].
Ahmed, Hashim U. ;
Dickinson, Louise ;
Charman, Susan ;
Weir, Shraddha ;
McCartan, Neil ;
Hindley, Richard G. ;
Freeman, Alex ;
Kirkham, Alex P. ;
Sahu, Mahua ;
Scott, Rebecca ;
Allen, Clare ;
Van der Meulen, Jan ;
Emberton, Mark .
EUROPEAN UROLOGY, 2015, 68 (06) :927-936
[4]   Focal therapy for localised unifocal and multifocal prostate cancer: a prospective development study [J].
Ahmed, Hashim U. ;
Hindley, Richard G. ;
Dickinson, Louise ;
Freeman, Alex ;
Kirkham, Alex P. ;
Sahu, Mahua ;
Scott, Rebecca ;
Allen, Clare ;
Van der Meulen, Jan ;
Emberton, Mark .
LANCET ONCOLOGY, 2012, 13 (06) :622-632
[5]   Magnetic resonance image-guided focal laser ablation in clinically localized prostate cancer: safety and efficacy [J].
Al-Hakeem, Yasser ;
Raz, Orit ;
Gacs, Zita ;
Maclean, Fiona ;
Varol, Celi .
ANZ JOURNAL OF SURGERY, 2019, 89 (12) :1610-1614
[6]  
Anttinen M, 2019, SCAND J UROL, V53, P303, DOI [10.1080/21681805.2019.1660707, 10.1080/21681805.2019.1685795]
[7]  
Azzouzi Abdel-Rahmene, 2017, Lancet Oncol, V18, pe188, DOI 10.1016/S1470-2045(17)30163-8
[8]   Padeliporfi n vascular-targeted photodynamic therapy versus active surveillance in men with low-risk prostate cancer (CLIN1001 PCM301): an open-label, phase 3, randomised controlled trial [J].
Azzouzi, Abdel-Rahmene ;
Vincendeau, Sebastien ;
Barret, Eric ;
Cicco, Antony ;
Kleinclauss, Francois ;
van der Poel, Henk G. ;
Stief, Christian G. ;
Rassweiler, Jens ;
Salomon, Georg ;
Solsona, Eduardo ;
Alcaraz, Antonio ;
Tammela, Teuvo T. ;
Rosario, Derek J. ;
Gomez-Veiga, Francisco ;
Ahlgren, Goran ;
Benzaghou, Fawzi ;
Gaillac, Bertrand ;
Amzal, Billy ;
Debruyne, Frans M. J. ;
Fromont, Gaelle ;
Gratzke, Christian ;
Emberton, Mark .
LANCET ONCOLOGY, 2017, 18 (02) :181-191
[9]  
Bakavicius A, 2022, INT BRAZ J UROL, V48, P263, DOI [10.1590/s1677-5538.ibju.2021.0091, 10.1590/S1677-5538.IBJU.2021.0091]
[10]   Targeted Focal Therapy for the Management of Organ Confined Prostate Cancer [J].
Barqawi, Al B. ;
Stoimenova, Diliana ;
Krughoff, Kevin ;
Eid, Khadijah ;
O'Donnell, Colin ;
Phillips, Jason M. ;
Crawford, E. David .
JOURNAL OF UROLOGY, 2014, 192 (03) :749-753