Selective Oxidation of the 4-Ethyl-3-methylcinnoline Methylene Group by Al2O3-Supported Chromium Oxide

被引：0
作者：
Chikunov, S. Yu. [1 ,2 ]
Balakina, E. A. [1 ]
Kulakov, I. V. [1 ,3 ]
机构：
[1] Tyumen State Univ, Inst Chem, Tyumen 625003, Russia
[2] Tyumen State Univ, Lab Theory & Optimizat Chem & Technol Proc, Tyumen 625003, Russia
[3] Tyumen State Univ, Lab Nat Inspired Chem Engn, Tyumen 625003, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2023年 / 93卷 / 04期
基金：
俄罗斯科学基金会;
关键词：
cinnoline derivatives; 4-ethyl-3-methylcinnoline; 3-methyl-4-acetylcinnoline; oxidizing systems; alumina; inorganic supports; CINNOLINE DERIVATIVES;
D O I：
10.1134/S1070363223040059
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The optimal conditions for the oxidation of the methylene group in 4-ethyl-3-methylcinnoline to the corresponding ketone, 3-methyl-4-acetylcinnoline, were selected. It was shown that preliminary deposition of 4-ethyl-3-methylcinnoline on some inorganic substrates has a significant effect both on the selectivity of the oxidation of only the methylene group and on a high degree of conversion to the target product.
引用
收藏
页码：800 / 806
页数：7
相关论文
共 20 条
  • [1] Immediate epoxidation of cyclohexene at room temperature using mesoporous flower-like NiO nanoparticles
    Abboud, Mohamed
    [J]. REACTION KINETICS MECHANISMS AND CATALYSIS, 2020, 131 (02) : 781 - 792
  • [2] Synthesis and biological evaluation of new quinazoline and cinnoline derivatives as potential atypical antipsychotics
    Alvarado, M
    Barceló, M
    Carro, L
    Masaguer, CF
    Raviña, E
    [J]. CHEMISTRY & BIODIVERSITY, 2006, 3 (01) : 106 - 117
  • [3] Bekhit A A, 2001, Boll Chim Farm, V140, P243
  • [4] Hepatoprotective Activity of Cichorium endivia L. Extract and Its Chemical Constituents
    Chen, Chao-Jie
    Deng, An-Jun
    Liu, Chang
    Shi, Rui
    Qin, Hai-Lin
    Wang, Ai-Ping
    [J]. MOLECULES, 2011, 16 (11): : 9049 - 9066
  • [5] Allylic oxidation of cyclohexene over ruthenium-doped titanium-pillared clay
    Dali, Ahmed
    Rekkab-Hammoumraoui, Ilhem
    Choukchou-Braham, Abderrahim
    Bachir, Redouane
    [J]. RSC ADVANCES, 2015, 5 (37) : 29167 - 29178
  • [6] Gautam N, 2010, INDIAN J CHEM B, V49, P830
  • [7] REACTIONS WITH HETEROCYCLES CONTAINING A 2-ACYL-2-PROPENONE STRUCTURE .3. PYRIDO[3,2-C] COUMARINS FROM 3-SUBSTITUTED 1-BENZOPYRANS AND ENAMINES
    HEBER, D
    [J]. ARCHIV DER PHARMAZIE, 1987, 320 (05) : 402 - 406
  • [8] Co/NHPI-mediated aerobic oxygenation of benzylic C-H bonds in pharmaceutically relevant molecules
    Hruszkewycz, Damian P.
    Miles, Kelsey C.
    Thiel, Oliver R.
    Stahl, Shannon S.
    [J]. CHEMICAL SCIENCE, 2017, 8 (02) : 1282 - 1287
  • [9] Design, Synthesis, Cytotoxic Activity and Apoptosis-inducing Action of Novel Cinnoline Derivatives as Anticancer Agents
    Kandeel, Manal M.
    Kamal, Aliaa M.
    Naguib, Bassem H.
    Hassan, Marwa S. A.
    [J]. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2018, 18 (08) : 1208 - 1217
  • [10] Synthesis of new representatives of 11,12-dihydro-5H-5,11-epoxybenzo[7,8]oxocino[4,3-b]pyridines - structural analogues of integrastatins A, B
    Kulakov, Ivan, V
    Stalinskaya, Alena L.
    Chikunov, Semyon Y.
    Gatilov, Yuri, V
    [J]. NEW JOURNAL OF CHEMISTRY, 2021, 45 (07) : 3559 - 3569
12