Indirect electrochemical reductive cyclization of o-halophenylacrylamides mediated by phenanthrene

被引：14

作者：

Zhou, Xue-Qi ^{[1
]}

Chen, Pei-Bo ^{[1
]}

Xia, Qiang ^{[1
]}

Xiong, Ting-Kai ^{[1
]}

Li, Xue-Jun ^{[1
]}

Pan, Ying-Ming ^{[3
]}

He, Mu-Xue ^{[2
]}

Liang, Ying ^{[1
]}

机构：

[1] Guilin Univ Elect Technol, Sch Life & Environm Sci, Guilin 541004, Guangxi, Peoples R China

[2] Guilin Med Univ, Guangxi Key Lab Environm Expos & Entire Lifecycle, Sch Publ Hlth, Guilin 541199, Guangxi, Peoples R China

[3] Guangxi Normal Univ, Sch Chem & Pharmaceut Sci, State Key Lab Chem & Mol Engn Med Resources, Guilin 541004, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2023年 / 10卷 / 08期

基金：

中国国家自然科学基金;

关键词：

RADICAL CYCLIZATION; INHIBITORS; DERIVATIVES;

D O I：

10.1039/d3qo00280b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3,4-Dihydroquinolone is an important drug and biological compound. o-Halophenylacrylamides were cyclized by two-electron reduction under electrochemical catalysis to obtain the corresponding 3,4-dihydroquinolinone products. This electrochemical cyclization improves the selectivity of the reaction when using phenanthrene as a reducing mediator. The mechanism study shows that phenanthrene has a good effect on the reaction, indicating that it is a good dielectric for electroreduction.

引用

页码：2039 / 2044

页数：6

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