YaHS: yet another Hi-C scaffolding tool

被引:278
作者
Zhou, Chenxi [1 ,2 ]
McCarthy, Shane A. [1 ,2 ]
Durbin, Richard [1 ,2 ]
机构
[1] Univ Cambridge, Dept Genet, Cambridge CB2 3EH, England
[2] Wellcome Sanger Inst, Wellcome Genome Campus, Cambridge CB10 1SA, England
基金
芬兰科学院;
关键词
GENOME ASSEMBLIES;
D O I
10.1093/bioinformatics/btac808
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We present YaHS, a user-friendly command-line tool for the construction of chromosome-scale scaffolds from Hi-C data. It can be run with a single-line command, requires minimal input from users (an assembly file and an alignment file) which is compatible with similar tools and provides assembly results in multiple formats, thereby enabling rapid, robust and scalable construction of high-quality genome assemblies with high accuracy and contiguity. Availability and implementation: YaHS is implemented in C and licensed under the MIT License. The source code, documentation and tutorial are available at .Supplementary informationare available at Bioinformatics online.
引用
收藏
页数:3
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