Prognostic value of serum albumin to creatinine ratio in patients undergoing carotid artery stenting

被引:0
作者
Karatas, Mesut [1 ]
Parsova, Kemal E. [2 ]
Keskin, Muhammed [3 ]
Ocal, Lutfi [1 ]
Dogan, Selami [4 ,6 ]
Keles, Nursen [5 ]
机构
[1] Univ Hlth Sci, Kartal Kosuyolu Yuksek Ihtisas Training & Res Hosp, Dept Cardiol, Istanbul, Turkiye
[2] Medicana Atasehir Hosp, Dept Cardiol, Istanbul, Turkiye
[3] Bahcesehir Univ, Fac Med, Dept Cardiol, Istanbul, Turkiye
[4] Malkara State Hosp, Tekirdag, Turkiye
[5] Univ Hlth Sci, Dr Siyami Ersek Thorac & Cardiovasc Surg Training, Dept Cardiol, Istanbul, Turkiye
[6] Malkara State Hosp, Pinar St 3, TR-59300 Tekirdag, Turkiye
关键词
Carotid arteries; Stents; Serum albumin; Creatinine; Stroke; ENDARTERECTOMY; INFLAMMATION; DISEASE; RISK;
D O I
10.23736/S0392-9590.24.05112-5
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Background: We aimed to investigate the prognostic value of serum albumin-to-creatinine ratio (sACR) in carotid artery stenting (CAS) patients regarding in -hospital and 5 -year outcomes. Methods: This is a retrospective study. Baseline characteristics were compared between patients by admission albumin to creatinine ratio and categorized accordingly: T1, T2 and T3. 609 patients were included in the study. Serum albumin and creatinine levels at hospital admission were used to calculate the sACR. The primary endpoint was all -cause mortality. MACE consisted of stroke, transient ischemic attack (TIA), myocardial infarction (MI) and death. All follow-up data were obtained from electronic medical records or by interview. The study was terminated after 60 months of follow-up. Results: Serum albumin levels were found to be significantly lower in T1, while creatinine was found to be significantly higher in T1. T1 has the lowest sACR while T3 has the highest. In hospital, ipsilateral stroke, major stroke, MI and death were significantly higher in T1. In long-term outcomes, ipsilateral stroke, major stroke, and death were significantly higher in T1. Conclusions: Low sACR values at hospital admission was independently associated with in -hospital and longterm mortality and major stroke in patients underwent CAS. (Cite this article: Karatas M, Parsova KE, Keskin M, Ocal L, Dogan S, Keles N. Prognostic value of serum albumin to creatinine ratio in patients undergoing carotid artery stenting. Int Angiol 2024 Apr 04. DOI: 10.23736/S0392-9590.24.05112-5)
引用
收藏
页码:290 / 297
页数:8
相关论文
共 25 条
[1]   Human serum albumin in cardiovascular diseases [J].
Arques, Stephane .
EUROPEAN JOURNAL OF INTERNAL MEDICINE, 2018, 52 :8-12
[2]   Editor's Choice- What do small serum creatinine changes tell us about outcomes after acute myocardial infarction? [J].
Auer, Johann ;
Verbrugge, Frederik H. ;
Lamm, Gudrun .
EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE, 2018, 7 (08) :739-742
[3]   Association of low serum albumin concentration and adverse cardiovascular events in stable coronary heart disease [J].
Chien, Shih-Chieh ;
Chen, Chun-Yen ;
Leu, Hsin-Bang ;
Su, Cheng-Huang ;
Yin, Wei-Hsian ;
Tseng, Wei-Kung ;
Wu, Yen-Wen ;
Lin, Tsung-Hsien ;
Chang, Kuan-Cheng ;
Wang, Ji-Hung ;
Wu, Chau-Chung ;
Yeh, Hung-I ;
Chen, Jaw-Wen .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2017, 241 :1-5
[4]   Carotid artery stenting compared with endarterectomy in patients with symptomatic carotid stenosis (International Carotid Stenting Study): an interim analysis of a randomised controlled trial [J].
Ederle, Joerg ;
Dobson, Joanna ;
Featherstone, Roland L. ;
Bonati, Leo H. ;
van der Worp, H. Bart ;
de Borst, Gert J. ;
Lo, T. Hauw ;
Gaines, Peter ;
Dorman, Paul J. ;
Macdonald, Sumaira ;
Lyrer, Philippe A. ;
Hendriks, Johanna M. ;
McCollum, Charles ;
Nederkoorn, Paul J. ;
Brown, Martin M. ;
Algra, A. ;
Bamford, J. ;
Beard, J. ;
Bland, M. ;
Bradbury, A. W. ;
Brown, M. M. ;
Clifton, A. ;
Gaines, P. ;
Hacke, W. ;
Halliday, A. ;
Malik, I. ;
Mas, J. L. ;
McGuire, A. J. ;
Sidhu, P. ;
Venables, G. ;
Bradbury, A. ;
Brown, M. M. ;
Clifton, A. ;
Gaines, P. ;
Collins, R. ;
Molynewc, A. ;
Naylor, R. ;
Warlow, C. ;
Ferro, J. M. ;
Thomas, D. ;
Bonati, L. H. ;
Coward, L. ;
Dobson, J. ;
Ederle, J. ;
Featherstone, R. F. ;
Tindall, H. ;
McCabe, D. J. H. ;
Wallis, A. ;
Brooks, M. ;
Chambers, B. .
LANCET, 2010, 375 (9719) :985-997
[5]   Atherosclerosis and inflammation: overview and updates [J].
Geovanini, Glaucylara Reis ;
Libby, Peter .
CLINICAL SCIENCE, 2018, 132 (12) :1243-1252
[6]   Prognostic Implications of Serum Albumin Levels in Patients With Acute Coronary Syndromes [J].
Gonzalez-Pacheco, Hector ;
Amezcua-Guerra, Luis M. ;
Sandoval, Julio ;
Martinez-Sanchez, Carlos ;
Ortiz-Leon, Xochitl A. ;
Pena-Cabral, Marco A. ;
Bojalil, Rafael .
AMERICAN JOURNAL OF CARDIOLOGY, 2017, 119 (07) :951-958
[7]   Serum albumin concentration and heart failure risk: The Health, Aging, and Body Composition Study [J].
Gopal, Deepa M. ;
Kalogeropoulos, Andreas P. ;
Georgiopoulou, Vasiliki V. ;
Tang, Wilson W. H. ;
Methvin, Amanda ;
Smith, Andrew L. ;
Bauer, Douglas C. ;
Newman, Anne B. ;
Kim, Lauren ;
Harris, Tamara B. ;
Kritchevsky, Stephen B. ;
Butler, Javed .
AMERICAN HEART JOURNAL, 2010, 160 (02) :279-285
[8]   The CAPTURE registry: Predictors of outcomes in carotid artery stenting with embolic protection for high surgical risk patients in the early post-approval setting [J].
Gray, William A. ;
Yadav, Jay S. ;
Verta, Patrick ;
Scicli, Andrea ;
Fairman, Ronald ;
Wholey, Mark ;
Hopkins, L. Nelson ;
Atkinson, Richard ;
Raabe, Rod ;
Barnwell, Stanley ;
Green, Richard .
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 2007, 70 (07) :1025-1033
[9]   SERUM-ALBUMIN ENHANCES THE IMPAIRMENT OF PLATELET-AGGREGATION WITH THROMBOXANE SYNTHASE INHIBITION BY INCREASING THE FORMATION OF PROSTAGLANDIN-D2 [J].
GRESELE, P ;
DECKMYN, H ;
HUYBRECHTS, E ;
VERMYLEN, J .
BIOCHEMICAL PHARMACOLOGY, 1984, 33 (13) :2083-2088
[10]   Cardiovascular Disease in Chronic Kidney Disease Pathophysiological Insights and Therapeutic Options [J].
Jankowski, Joachim ;
Floege, Juergen ;
Fliser, Danilo ;
Boehm, Michael ;
Marx, Nikolaus .
CIRCULATION, 2021, 143 (11) :1157-1172