Choroidal vascularity index in adult patients with familial meditteranean fever

被引：3

作者：

Timur, Inci Elif Erbahceci ^{[1
]}

Atalar, Ebru ^{[2
]}

Maras, Yuksel ^{[2
]}

Seker, Esra Dag ^{[1
]}

Yuzbasioglu, Sema ^{[3
]}

Ugurlu, Nagihan ^{[3
]}

机构：

[1] Minist Hlth, Ankara City Hosp, Ophthalmol Clin, Ankara, Turkiye

[2] Minist Hlth, Ankara City Hosp, Rheumatol Clin, Ankara, Turkiye

[3] Yildirim Beyazit Univ, Ankara City Hosp, Minist Hlth, Ophthalmol Clin,Fac Med,Dept Ophthalmol, Ankara, Turkiye

来源：

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY | 2023年 / 42卷

关键词：

Binarized image; Choroidal thickness; Choroidal vascularity index; Chronic inflammation; Familial mediterranean fever; OCT; MEDITERRANEAN FEVER; THICKNESS; CHILDREN; MUTATIONS; DISEASES; MARKERS; SERIES; GENE;

D O I：

10.1016/j.pdpdt.2023.103350

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Purpose: This study aimed to evaluate choroidal vascular status by the choroidal vascularity index (CVI) in adult patients with familial Mediterranean fever (FMF) in remission period.Materials-methods: 86 patients diagnosed with FMF and 54 healthy controls were recruited in this study. Retinal, ganglion cell complex and peripapillary retinal nerve fibre layer thicknesses were obtained using Spectralis domain-optical coherence (SD-OCT) tomography. Choroid images were obtained with the enhanced depth im-aging mode of SD-OCT, and binarization was applied to the images using ImageJ software. CVI was described as the proportion of the luminal area to the total choroidal area. Blood-derived inflammation markers were calculated by the complete blood count.Results: The subfoveal choroidal thickness and nasal and temporal directions from fovea centralis at 500 mu m, 1000 mu m and 1500 mu m were reduced in patients with FMF in comparison to healthy controls (p<0.001, each comparison). CVI was significantly decreased in patients with FMF compared to controls (62.28 +/- 2.2 and 64.79 +/- 4.3, p<0.001).Conclusion: We concluded that the choroidal vasculature structure may be affected prior to retinal changes in patients with FMF.

引用

页数：6

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