Trio Role of Deep Eutectic Solvents in the Green Synthesis of 1,4-Dihydropyridine Synthesis via Hantzsch Reaction

被引:7
|
作者
Kumar, Gobind [1 ]
Bhargava, Gaurav [1 ]
Kumar, Rupesh [1 ]
机构
[1] IKG Punjab Tech Univ, Dept Chem Sci, Kapurthala 144603, Punjab, India
关键词
Deep eutectic solvent; green chemistry; Hantzsch reaction; 14-dihydropyridine; metal free catalysis; ONE-POT SYNTHESIS; EFFICIENT SYNTHESIS; DERIVATIVES; CATALYSTS; METRICS; POLYHYDROQUINOLINES; SYSTEMS;
D O I
10.1080/10406638.2022.2133905
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Here, we have reported a novel deep eutectic solvent (DES) with tremendous activity for the synthesis of dihydropyridines. DESs have played a trio role in the reaction. It acts as a green catalyst, solvent, and in-situ substrate in this chemical reaction. This method offers various advantages such as metal-free catalysis, green solvent, high yields of the products, and short reaction time.
引用
收藏
页码:7238 / 7251
页数:14
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